Evidence map›Paper›PMID 36344838›Full record

ArticleEuropean radiology experimental2022

NAVIGATOR: an Italian regional imaging biobank to promote precision medicine for oncologic patients.

Rita Borgheresi, Andrea Barucci, Sara Colantonio, Gayane Aghakhanyan, Massimiliano Assante, Elena Bertelli, Emanuele Carlini, Roberto Carpi, Claudia Caudai, Diletta Cavallero and 33 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology experimental, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors at 8 institutions in 2 countries.

Rita BorgheresiAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Andrea Barucci"Nello Carrara" Institute of Applied Physics - IFAC of the National Research Council - CNR, Florence, Italy.
Sara ColantonioInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Gayane AghakhanyanAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy. gayane.aghakhanyan@med.unipi.it.ORCID 0000-0001-5152-497X
Massimiliano AssanteInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Elena BertelliDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Emanuele CarliniInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Roberto CarpiAzienda USL Toscana Centro, Florence, Italy.
Claudia CaudaiInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Diletta CavalleroAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Dania CioniAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Roberto CirilloInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Valentina Colcelli"Nello Carrara" Institute of Applied Physics - IFAC of the National Research Council - CNR, Florence, Italy.
Andrea Dell'AmicoInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Domnico Di GangiInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Paola Anna ErbaAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Lorenzo FaggioniAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Zeno FalaschiAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Michela GabelloniAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Rosa GiniAzienda Regionale di Sanità, Florence, Italy.
Lucio LeliiInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Pietro LiòDepartment of Computer Science and Technology of the University of Cambridge, Cambridge, UK.
Antonio Lorito"Nello Carrara" Institute of Applied Physics - IFAC of the National Research Council - CNR, Florence, Italy.
Silvia LucariniDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Paolo ManghiInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Francesco MangiacrapaInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Chiara Marzi"Nello Carrara" Institute of Applied Physics - IFAC of the National Research Council - CNR, Florence, Italy.
Maria Antonietta MazzeiUnit of Diagnostic Imaging, Department of Medical, Surgical and Neurosciences and of Radiological Sciences, University of Siena, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.
Laura MercatelliDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Antonella Mirabile"Nello Carrara" Institute of Applied Physics - IFAC of the National Research Council - CNR, Florence, Italy.
Francesco MungaiDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Vittorio MieleDepartment of Radiology, Careggi University Hospital, Florence, Italy.
Maristella OlmastroniAzienda USL Toscana Centro, Florence, Italy.
Pasquale PaganoInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Fabiola PaiarAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Giancarlo PanichiInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Maria Antonietta PascaliInstitute of Information Science and Technologies - ISTI of the National Research Council - CNR, Pisa, Italy.
Filippo PasquinelliAzienda USL Toscana Centro, Florence, Italy.
Jorge Eduardo ShortredeAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Lorenzo TumminelloAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
Luca VolterraniUnit of Diagnostic Imaging, Department of Medical, Surgical and Neurosciences and of Radiological Sciences, University of Siena, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.
Emanuele NeriAcademic Radiology, Department of Translational Research and of New Surgical and Medical Technology, University of Pisa, 56126, Pisa, Italy.
NAVIGATOR Consortium Group
Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo" · ITUniversity of Pisa · ITAzienda Ospedaliero-Universitaria Careggi · ITNello Carrara Institute of Applied Physics · ITAzienda Usl Toscana Centro · ITUniversity of Siena · ITAgenzia Regionale di Sanità della Toscana · ITUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NAVIGATOR is an Italian regional project boosting precision medicine in oncology with the aim of making it more predictive, preventive, and personalised by advancing translational research based on quantitative imaging and integrative omics analyses. The project's goal is to develop an open imaging biobank for the collection and preservation of a large amount of standardised imaging multimodal datasets, including computed tomography, magnetic resonance imaging, and positron emission tomography data, together with the corresponding patient-related and omics-related relevant information extracted from regional healthcare services using an adapted privacy-preserving model. The project is based on an open-source imaging biobank and an open-science oriented virtual research environment (VRE). Available integrative omics and multi-imaging data of three use cases (prostate cancer, rectal cancer, and gastric cancer) will be collected. All data confined in NAVIGATOR (i.e., standard and novel imaging biomarkers, non-imaging data, health agency data) will be used to create a digital patient model, to support the reliable prediction of the disease phenotype and risk stratification. The VRE that relies on a well-established infrastructure, called D4Science.org, will further provide a multiset infrastructure for processing the integrative omics data, extracting specific radiomic signatures, and for identification and testing of novel imaging biomarkers through big data analytics and artificial intelligence.

Indexed as

Artificial IntelligencePrecision MedicineBiological Specimen BanksBiomarkersPositron-Emission TomographyBiomarkersArtificial intelligenceBiobanksBiomarkersPrecision medicineRadiomics

Identifiers

PMID36344838
PMCPMC9640522
OpenAlexW4308382753

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.