ArticleNature chemistry2022
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO
Article in Nature chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 49 citations in OpenAlex.
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- A Para-Selective Kolbe-Schmitt Reaction.Angewandte Chemie (International ed. in English) · 2026Article
- Tailored amination enables switchable synthesis of α- and γ-amino acid derivatives from extended quinone methides.Nature communications · 2025Article
- Pyridoxal-Inspired Photo-Decarboxylase Catalysis: Photochemical Decarboxylation of Unprotected Amino Acids.Angewandte Chemie (International ed. in English) · 2025Article
- Electrochemical Synergistic Ni/Co-Catalyzed Carbonylative Cross-Electrophile Coupling of Aryl and Alkyl Halides with CO.JACS Au · 2025Article
- Carbon isotopic labelling of carboxylic acids enabled by organic photoredox-catalysed cyanation.Nature synthesis · 2025Article
- A practical guide for the preparation of C1-labeled α-amino acids using aldehyde catalysis with isotopically labeled CONature protocols · 2024Article
- A metal-catalysed functional group metathesis approach to the carbon isotope labelling of carboxylic acids.Nature chemistry · 2024Article
- Carbon isotope exchange for pharmaceutical radiolabelling through metal-catalysed functional group metathesis.Nature chemistry · 2024Article
- Late-Stage Isotopic Exchange of Primary Amines.Journal of the American Chemical Society · 2023Article
- Molecular Editing of Pyrroles via a Skeletal Recasting Strategy.ACS central science · 2023Article
- Highlight selection of radiochemistry and radiopharmacy developments by editorial board.EJNMMI radiopharmacy and chemistry · 2023Review
- Recent Developments in Carbon-11 Chemistry and Applications for First-In-Human PET Studies.Molecules (Basel, Switzerland) · 2023Review
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The isotopic labelling of small molecules is integral to drug development and for understanding biochemical processes. The preparation of carbon-labelled α-amino acids remains difficult and time consuming, with established methods involving label incorporation at an early stage of synthesis. This explains the high cost and scarcity of C-labelled products and presents a major challenge in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.