ArticleNature metabolism2022
ADRA1A-Gα
Open access · hybridAbstract read
In one paragraph
Article in Nature metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 52 citations in OpenAlex.
- Exosome trafficking is a key regulator of adipocyte thermogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- ASIV Attenuates Cisplatin-Induced Proximal Tubular Injury by Enhancing Mitochondrial Biogenesis and Mitophagy Through the ADRA1A/AMPK/FOXO3A Pathway.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- ALKBH5 activates creatine-driven thermogenesis by stabilizing CKB mRNA in response to cold.Nature metabolism · 2026Article
- Improving incretin-mediated body weight loss via energy expenditure.Trends in endocrinology and metabolism: TEM · 2026Review
- Junctophilin-2-orchestrated calcium signalosome regulates brown adipocyte thermogenesis and energy metabolism.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Legacy Effects of Early β-Adrenergic Stimulation Program Adipose Plasticity and Confer Metabolic Resilience in Obesity.bioRxiv : the preprint server for biology · 2026Article
- Glycerol is a new ally for heat production and bone health.Nature metabolism · 2026Article
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- Myofibroblasts Induce Neuroplasticity to Promote Pancreatic Inflammation and Cancer Progression.Cancer discovery · 2026Article
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- PTG-Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PMAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Thermoregulatory adaptations to cold in C3H/HeJ mice are independent of ADRB3 signaling.Scientific reports · 2026Article
- ERRγ impedes neuroendocrine prostate cancer development.Genes & development · 2026Article
- Review
- Cold exposure induces the constitutively active thermogenic receptor, GPR3, via ERRα and ERRγ.Molecular metabolism · 2026Article
- Adipose tissue ageing: implications for metabolic health and lifespan.Nature reviews. Endocrinology · 2025Review
- Molecular mechanisms of UCP1-independent thermogenesis: the role of futile cycles in energy dissipation.Journal of physiology and biochemistry · 2025Review
- Creatinine promotes adipose tissue wasting in chronic kidney disease via creatine and futile creatine cycle.Molecular metabolism · 2025Article
- Creatine kinase B mediates UCP1-independent beige fat thermogenesis via the futile creatine cycle in mice.Molecular metabolism · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors at 13 institutions in 5 countries.
Janane F RahbaniRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-4598-4683
Charlotte ScholtesRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-4982-5308
Damien M LagardeRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Mohammed F HussainRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Anna RoeslerRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Christien B DykstraRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-3157-5515
Jakub BunkRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Bozena SamborskaRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Shannon L O'BrienInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
Emma TrippInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0003-1425-5541
Alain PacisRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.
Anthony R AngueiraInstitute for Diabetes, Obesity & Metabolism and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Olivia S JohansenNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
Jessica CinkornpuminDepartment of Biochemistry, McGill University, Montreal, Quebec, Canada.
Ishtiaque HossainDepartment of Biochemistry, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-4494-0366
Matthew D LynesMaine Medical Center Research Institute, Scarborough, ME, USA.ORCID http://orcid.org/0000-0003-0746-0854
Yang ZhangSection on Integrative Physiology and Metabolism, Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Andrew P WhiteDepartment of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
William A PastorRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-4176-5299
Maria ChondronikolaDepartment of Nutrition and Radiology, University of California, Davis, Davis, CA, USA.
Labros SidossisDepartment of Kinesiology and Health, School of Arts and Sciences, Rutgers University, New Brunswick, NJ, USA.
Samuel KleinDivision of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO, USA.
Anastasia KralliDepartment of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Aaron M CypessDiabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-5570-9346
Steen B PedersenSteno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Aarhus N, Denmark.ORCID http://orcid.org/0000-0002-7838-8063
Niels JessenSteno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Aarhus N, Denmark.ORCID http://orcid.org/0000-0001-5613-7274
Yu-Hua TsengSection on Integrative Physiology and Metabolism, Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-2053-9559
Zachary Gerhart-HinesNovo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2981-4991
Patrick SealeInstitute for Diabetes, Obesity & Metabolism and Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-7119-1615
Davide CalebiroInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.ORCID http://orcid.org/0000-0002-3811-1553
Vincent GiguèreRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0001-9567-3694
Lawrence KazakRosalind & Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada. lawrence.kazak@mcgill.ca.ORCID http://orcid.org/0000-0002-7591-2544
McGill University · CAUniversity of Birmingham · GBJoslin Diabetes Center · USSteno Diabetes Centers · DKUniversity of Copenhagen · DKUniversity of Pennsylvania · USBeth Israel Deaconess Medical Center · USHarokopio University of Athens · GRJohns Hopkins University · USMaine Medical Center · USNational Institutes of Health · USRutgers, The State University of New Jersey · USWashington University in St. Louis · US
Funding
SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5MWashington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 1999 to 2026
$30.2MWU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI James Alexander Fitzpatrick · 2013 to 2026
$27.1MUCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6MFibroblast Growth Factor and Energy MetabolismR01DK102898 · NIDDK · JOSLIN DIABETES CENTER · PI TSENG, YU-HUA · 2015 to 2024
$4.1MTranscriptional and epigenetic regulation of thermogenic adipocyte programR01DK132469 · NIDDK · JOSLIN DIABETES CENTER · PI Yu-Hua Tseng · 2022 to 2026
$3.0MThe Lipidomics of Adipose Tissue ThermogenesisK01DK111714 · NIDDK · MAINEHEALTH · PI LYNES, MATTHEW D · 2017 to 2021
$804kMedical Research CouncilNIDDK NIH HHS K01 DK111714NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK036836NIDDK NIH HHS P30 DK056341NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK102898NIDDK NIH HHS R01 DK132469Wellcome TrustWellcome Trust 212313/Z/18/Z
Abstract
Noradrenaline (NA) regulates cold-stimulated adipocyte thermogenesis
Indexed as
CreatineThermogenesisAdipocytesCreatine KinaseEnergy MetabolismCreatineCreatine Kinase
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.