Evidence map›Paper›PMID 36344673›Full record

ArticleScientific reports2022

Investigating the effects of low intensity visible light on human keratinocytes using a customized LED exposure system.

Emily Sutterby, Chanly Chheang, Peter Thurgood, Khashayar Khoshmanesh, Sara Baratchi, Elena Pirogova

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
  6. Wound healing and photodynamic potential ofFrontiers in pharmacology · 2025
    Article
  7. Review of sensory systems deployed by epidermal keratinocytes.Frontiers in cell and developmental biology · 2025
    Review
  8. Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emily SutterbySchool of Engineering, RMIT University, Melbourne, VIC, Australia.
Chanly ChheangSchool of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, Australia.
Peter ThurgoodSchool of Engineering, RMIT University, Melbourne, VIC, Australia.
Khashayar KhoshmaneshSchool of Engineering, RMIT University, Melbourne, VIC, Australia.
Sara Baratchi *School of Health and Biomedical Sciences, RMIT University, Bundoora, VIC, Australia.
Elena Pirogova *School of Engineering, RMIT University, Melbourne, VIC, Australia. elena.pirogova@rmit.edu.au.
RMIT University · AU

Funding

Australian National Health and Medical Research Council CRE APP1135076Australian Research Council for Discovery Grant DP200101248
6 · The paper itself

Abstract

Photobiomodulation (PBM) refers to the use of light to modulate cellular processes, and has demonstrated utility in improving wound healing outcomes, and reducing pain and inflammation. Despite the potential benefits of PBM, the precise molecular mechanisms through which it influences cell behavior are not yet well understood. Inconsistent reporting of key light parameters has created uncertainty around optimal exposure profiles. In addition, very low intensities of light, < 0.1 J/cm

Indexed as

Low-Level Light TherapyCell ProliferationHumansKeratinocytesLightReactive Oxygen SpeciesWound HealingReactive Oxygen Species

Identifiers

PMID36344673
PMCPMC9640685
OpenAlexW4308459818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.