Evidence map›Paper›PMID 36344523›Full record

ArticleNPJ vaccines2022

Feasibility of novel adult tuberculosis vaccination in South Africa: a cost-effectiveness and budget impact analysis.

Sahan Jayawardana, Chathika K Weerasuriya, Puck T Pelzer, Janet Seeley, Rebecca C Harris, Michele Tameris, Dereck Tait, Richard G White, Miqdad Asaria

Abstract read
In one paragraph

Article in NPJ vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sahan JayawardanaDepartment of Health Policy, London School of Economics (LSE), London, UK. s.a.jayawardana@lse.ac.uk.ORCID http://orcid.org/0000-0001-7081-3910
Chathika K WeerasuriyaTB Modelling Group, TB Centre and Centre for the Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0001-7364-1026
Puck T PelzerTB Modelling Group, TB Centre and Centre for the Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Janet SeeleyDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Rebecca C HarrisTB Modelling Group, TB Centre and Centre for the Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Michele TamerisSouth African Tuberculosis Vaccine Initiative (SATVI), Department of Pathology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT), Cape Town, South Africa.ORCID http://orcid.org/0000-0002-7983-7203
Dereck TaitIndependent consultant, Cape Town, South Africa.
Richard G WhiteTB Modelling Group, TB Centre and Centre for the Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0003-4410-6635
Miqdad AsariaDepartment of Health Policy, London School of Economics (LSE), London, UK.ORCID http://orcid.org/0000-0002-3538-4417

Funding

Defining drivers of TB transmission in the era of universal ART, and implications for finding the walking wellR01AI147321 · NIAID · LONDON SCH/HYGIENE & TROPICAL MEDICINE · PI GRANT, ALISON · 2019 to 2024
$2.3M
NIAID NIH HHS R01 AI147321Wellcome Trust
6 · The paper itself

Abstract

Early trials of novel vaccines against tuberculosis (TB) in adults have suggested substantial protection against TB. However, little is known about the feasibility and affordability of rolling out such vaccines in practice. We conducted expert interviews to identify plausible vaccination implementation strategies for the novel M72/AS01

Identifiers

PMID36344523
PMCPMC9640704

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.