Evidence map›Paper›PMID 36344308›Full record

Trial reportNutrition, metabolism, and cardiovascular diseases : NMCD2023

Device-guided slow breathing alters postprandial oxidative stress in young adult males: A randomized sham-controlled crossover trial.

Stacy D Hunter, Luciano Bernardi, Matthew J McAllister, Dinesh John, Mitra Rahimi, Micqauella R Lopez

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04864184 (The Effects of Different Breathing Styles on Post High-Fat Meal Blood Vessel Function), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04864184 nacompletednot on this map

The Effects of Different Breathing Styles on Post High-Fat Meal Blood Vessel Function

TypeinterventionalSponsorTexas State UniversityRan2020 to 2021Enrolled21ConditionsHealthyArmsNormal physiologic rate breathing, Slow breathing
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Stacy D HunterTexas State University Department of Health & Human Performance, San Marcos, TX, USA. Electronic address: stacy.d.hunter@gmail.com.
Luciano BernardiFolkhälsan Institute of Genetics, Folkhälsan Research Center, University of Helsinki, Helsinki, Finland; Abdominal Center Nephrology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; Research Program Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland.
Matthew J McAllisterTexas State University Department of Health & Human Performance, San Marcos, TX, USA.
Dinesh JohnNortheastern University Department of Health Sciences, Boston, MA, USA.
Mitra RahimiTexas State University Department of Health & Human Performance, San Marcos, TX, USA.
Micqauella R LopezTexas State University Department of Health & Human Performance, San Marcos, TX, USA.
Texas State University · USNortheastern University · USUniversity of Helsinki · FI

Funding

Yoga Postures and Slow Deep Breathing in Altering Mechanistic Outcomes in HypertensionR21AT011399 · NCCIH · TEXAS STATE UNIVERSITY · PI HUNTER, STACY DENISE · 2022 to 2023
$408k
NCCIH NIH HHS R21 AT011399
6 · The paper itself

Abstract

BACKGROUND AND

aimsSlow, deep breathing (SDB) lowers blood pressure (BP) though the underlying mechanisms are unknown. Redox improvements could facilitate hemodynamic adjustments with SDB though this has not been investigated. The purpose of this randomized, sham-controlled trial was to examine the acute effects of SDB on oxidative stress and endothelial function during a physiological perturbation (high-fat meal) known to induce oxidative stress. METHODS AND

resultsSeventeen males (ages 18-35 years) were enrolled, and anthropometric measurements and 7-day physical activity monitoring were completed. Testing sessions consisted of 24-h diet recalls (ASA24), blood sample collection for superoxide dismutase (SOD) and thiobarbituric acid reactive substances (TBARS) analysis, and flow-mediated dilation (FMD). High-fat meals were ingested and 2-min breathing exercises (SDB or sham control breathing) were completed every 15 min during the 4-h postprandial phase. Blood sample collection and FMD were repeated 1-, 2-, and 4-h post meal consumption. Mean body mass index and step counts were 25.6 ± 4.3 kg/m

conclusionsFindings from the current investigation suggest that SDB alters postprandial redox in the absence of changes in endothelial function in young, healthy males. CLINICAL TRIAL REGISTRATION NUMBER: NCT04864184. CLINICAL TRIALS IDENTIFIER: NCT04864184.

Indexed as

Blood GlucoseDietAdolescentAdultCross-Over StudiesEndothelium, VascularHumansMaleOxidative StressPostprandial PeriodThiobarbituric Acid Reactive SubstancesYoung AdultBlood GlucoseThiobarbituric Acid Reactive SubstancesEndothelial functionOxidative stressSlow breathing

Identifiers

PMID36344308
PMCPMC9812884
OpenAlexW4304127762

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.