Evidence map›Paper›PMID 36344109›Full record

Observational studyOpen heart2022

Changes in platelet function and coagulation after transcatheter aortic valve implantation evaluated with thromboelastography.

Mae Harada, Takeyuki Sajima, Taichi Onimaru, Takahiro Honjo, Hirofumi Hioki, Yusuke Watanabe, Shigehito Sawamura

Abstract readObservational Study
In one paragraph

Observational study in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Fibrin clot strength is associated with increased risk of major adverse cardiac events after TAVR.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mae HaradaDepartment of Anaesthesiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan nkzwmae@gmail.com.ORCID 0000-0002-6103-3194
Takeyuki SajimaDepartment of Anaesthesiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan.
Taichi OnimaruDepartment of Anaesthesiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan.
Takahiro HonjoDepartment of Anaesthesiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan.
Hirofumi HiokiDepartment of Cardiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan.ORCID 0000-0001-7189-8450
Yusuke WatanabeDepartment of Cardiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan.ORCID 0000-0003-2297-5303
Shigehito SawamuraDepartment of Anaesthesiology, Teikyo University Hospital, Itabashi-ku, Tokyo, Japan.ORCID 0000-0002-8505-3851

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe possibility of hypercoagulability during the perioperative period of transcatheter aortic valve implantation (TAVI) has been noted; however, there is still a controversy regarding the appropriate perioperative antithrombotic therapy. The study investigated coagulation and platelet functions during the TAVI perioperative period using thromboelastography (TEG) 6s platelet mapping.

methodsA prospective observational study was conducted on 25 patients undergoing TAVI. TEG platelet mapping was performed at three time points: on admission to the operating room (before heparinisation), on postoperative day (POD) 1 and on POD 3. Perioperative changes observed included: maximum clot strength (MA

resultsMA

conclusionsIn this study involving TEG platelet mapping, coagulation capacity increased while platelet function decreased, resulting in antithrombotic change for 3 days after TAVI. The ADP receptor system may be implicated in the decreased platelet function. These results may be useful for considering optimal perioperative antithrombotic therapy in TAVI.

Indexed as

Transcatheter Aortic Valve ReplacementAdenosine DiphosphateFibrinolytic AgentsHumansPlatelet Aggregation InhibitorsThrombelastographyAdenosine DiphosphateFibrinolytic AgentsPlatelet Aggregation InhibitorsAortic Valve StenosisHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve Replacement

Identifiers

PMID36344109
PMCPMC9644365

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.