Evidence map›Paper›PMID 36344007›Full record

ArticleBMJ open2022

Agreement between the laboratory-based and non-laboratory-based WHO cardiovascular risk charts: a cross-sectional analysis of a national health survey in Peru.

Wilmer Cristobal Guzman-Vilca, Gustavo A Quispe-Villegas, Fritz Fidel Váscones Román, Antonio Bernabe-Ortiz, Rodrigo M Carrillo-Larco

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Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wilmer Cristobal Guzman-VilcaSchool of Medicine 'Alberto Hurtado', Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0002-2194-8496
Gustavo A Quispe-VillegasSchool of Medicine 'Alberto Hurtado', Universidad Peruana Cayetano Heredia, Lima, Peru.
Fritz Fidel Váscones RománSchool of Medicine 'Alberto Hurtado', Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0001-9564-0710
Antonio Bernabe-OrtizCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID 0000-0002-6834-1376
Rodrigo M Carrillo-LarcoCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru rcarrill@ic.ac.uk.ORCID 0000-0002-2090-1856

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveTo determine the agreement between the cardiovascular disease (CVD) risk predictions computed with the WHO non-laboratory-based model and laboratory-based model in a nationally representative sample of Peruvian adults.

designCross-sectional analysis of a national health survey.

methodsAbsolute CVD risk was computed with the 2019 WHO laboratory-based and non-laboratory-based models. The risk predictions from both models were compared with Bland-Altman plots, Lin's concordance coefficient correlation (LCCC), and kappa statistics, stratified by sex, age, body mass index categories, smoking and diabetes status.

results663 people aged 30-59 years were included in the analysis. Overall, there were no substantial differences between the mean CVD risk computed with the laboratory-based model 2.0% (95% CI 1.8% to 2.2%) and the non-laboratory-based model 2.0% (95% CI 1.8% to 2.1%). In the Bland-Altman plots, the limits of agreement were the widest among people with diabetes (-0.21; 4.37) compared with people without diabetes (-1.17; 0.95). The lowest agreement as per the LCCC was also seen in people with diabetes (0.74 (95% CI 0.63 to 0.82)), the same was observed with the kappa statistic (kappa=0.36). In general, agreement between the scores was appropriate in terms of clinical significance.

conclusionsThe absolute cardiovascular predicted risk was similar between the laboratory-based and non-laboratory-based 2019 WHO cardiovascular risk models. Pending validation from longitudinal studies, the non-laboratory-based model (instead of the laboratory-based) could be used when assessing CVD risk in Peruvian population.

Indexed as

Cardiovascular DiseasesDiabetes MellitusAdultCross-Sectional StudiesHealth SurveysHeart Disease Risk FactorsHumansPeruRisk AssessmentRisk FactorsWorld Health Organizationadult cardiologycardiac epidemiologyepidemiology

Identifiers

PMID36344007
PMCPMC9644334

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