ArticleChest2023
Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort.
Article in Chest, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01969344 (Subpopulations and Intermediate Outcome Measures in COPD Study), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Subpopulations and Intermediate Outcome Measures in COPD Study
Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Persistently low blood eosinophils identify a high-risk phenotype in COPD.BMC pulmonary medicine · 2026Article
- Resident eosinophils in patients with chronic obstructive pulmonary disease: a pilot study.Frontiers in medicine · 2026Article
- Persistent and unstable eosinophil levels in the sputum and blood: impact on the clinical prognosis of patients with chronic obstructive pulmonary disease.Journal of thoracic disease · 2025Article
- Stability of blood eosinophils during acute exacerbations in patients with chronic obstructive pulmonary disease.BMC pulmonary medicine · 2025Article
- Type 2 inflammation in chronic obstructive pulmonary disease: A promising treatable trait and practice recommendations.Chinese medical journal pulmonary and critical care medicine · 2025Article
- Diagnosing Type 2 Inflammation in COPD: Comparison of Blood and Sputum Eosinophil Assessment in the University of California Los Angeles COPD Phenotyping Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Low levels of DNA repair enzyme NEIL2 May exacerbate inflammation and genomic damage in subjects with stable COPD and during severe exacerbations.Respiratory research · 2025Article
- Observational
- Blood eosinophils levels in a Colombian cohort of biomass-and tobacco-related COPD patients.Frontiers in medicine · 2024Article
- Finding the Right Biological: Eosinophil Subset Differences in Asthma and Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2023Article
Corrections and comments
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Authors and funding
23 authors at 14 institutions in 1 country.
Funding
Abstract
backgroundThe Global Initiative for Chronic Obstructive Lung Disease (GOLD) considers blood eosinophil counts < 100 cells/μL (BEC RESEARCH QUESTION: Are there differences between GOLD group D patients with high BEC and those with low BEC regarding baseline characteristics and longitudinal outcomes? STUDY DESIGN AND
methodsWe used multivariable mixed models and logistic regression to contrast clinical characteristics and outcomes of BEC
resultsWe identified n = 485 with BEC
interpretationIn non-ICS-treated GOLD group D COPD, people with BEC CLINICAL
trial registrationClinicalTrials.gov; No.: NCT01969344; URL: www. CLINICALTRIALS: gov.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.