ArticleGut microbes
Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes.
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Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
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Who cites it
40 citing papers in PubMed, 56 citations in OpenAlex.
- Article
- The urinary pathobiont Actinobaculum massiliense can generate androgens via the dirAB pathway.Nature communications · 2026Article
- Characterization of an NADPH-dependent 17β-hydroxysteroid dehydrogenase from a urinary tract bacterial isolate.The Journal of steroid biochemistry and molecular biology · 2026Article
- The Collaborative Collapse: Bile Acid Dysmetabolism as a Central Pathogenic Driver in Canine and Feline Multi-Systemic Disorders-From Mechanisms to Precision Therapeutics.Veterinary sciences · 2026Review
- Commensal Microbiota and Reproductive Health in Livestock: Mechanisms, Cross-System Crosstalk, and Precision Strategies.Animals : an open access journal from MDPI · 2026Review
- Microbial transformation of secondary bile acids: roles in gut ecology and autoimmune diseases.Frontiers in immunology · 2026Review
- Acute gastrointestinal graft-versus-host disease is associated with reductions of secondary bile acids following allogeneic hematopoietic cell transplantation.Frontiers in microbiology · 2026Article
- BileActome reveals community-assembled bile acid metabolism in the rumen microbiome.ISME communications · 2026Article
- The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia.Gut microbes · 2025Article
- Metaflammation's Role in Systemic Dysfunction in Obesity: A Comprehensive Review.International journal of molecular sciences · 2025Review
- Biological Actions of Bile Acids via Cell Surface Receptors.International journal of molecular sciences · 2025Review
- Bile acid and microbiome interactions in the developing child.Journal of pediatric gastroenterology and nutrition · 2025Review
- Pangenome Analysis ofMicroorganisms · 2025Article
- Secondary Bile Acid Derivatives Are Contributors to the Fecal Bile Acid Pool and Associated With Bile Acid-Modulating Nutrients.The Journal of nutrition · 2025Article
- Clostridium scindens: history and current outlook for a keystone species in the mammalian gut involved in bile acid and steroid metabolism.FEMS microbiology reviews · 2025Review
- Article
- Effect of supplementation withFrontiers in microbiology · 2025Article
- Interplay between bile acids, gut microbiota, and the tumor immune microenvironment: mechanistic insights and therapeutic strategies.Frontiers in immunology · 2025Review
- Carcinogenic and anticancer activities of microbiota-derived secondary bile acids.Frontiers in oncology · 2025Review
- Influence of gut flora on diabetes management after kidney transplantation.BMC nephrology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 9 institutions in 4 countries.
Jae Won LeeCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Elise S CowleyDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
Patricia G WolfCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Heidi L DodenCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Tsuyoshi MuraiSchool of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan.
Kelly Yovani Olivos CaicedoDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Lindsey K LyCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Furong SunMass Spectrometry Laboratory, School of Chemical Sciences, University of Illinois Urbana-Champaign, IL, USA.
Hajime TakeiJunshin Clinic Bile Acid Institute, Tokyo, Japan.
Hiroshi NittonoJunshin Clinic Bile Acid Institute, Tokyo, Japan.
Steven L DanielDepartment of Biological Sciences, Eastern Illinois University, Charleston, IL, USA.
Isaac CannCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
H Rex GaskinsCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Karthik AnantharamanDepartment of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.
João M P AlvesDepartment of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Jason M RidlonCarl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
University of Illinois Urbana-Champaign · USTokyo Junshin University · JPUniversity of Wisconsin–Madison · USEastern Illinois University · USHealth Sciences University of Hokkaido · JPInstitute of Biomedical Science · GBUniversidade de São Paulo · BRUrbana University · USVirginia Commonwealth University · US
Funding
Research Training for Computation and Informatics in Biology and MedicineT15LM007359 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI Mark W. Craven, Colin Noel Dewey · 2002 to 2026
$22.6MUIC CANCER PREVENTION &CONTROL RESEARCH TRAINING GRANTR25CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FITZGIBBON, MARIAN L. · 1992 to 2017
$8.2MIntegrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5MCancer Health Equity Career Development ProgramT32CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Marian L. Fitzgibbon · 2018 to 2026
$3.0MDiet modulation of bacterial sulfur & bile acid metabolism and colon cancer riskR01CA204808 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GASKINS, REX, MUTLU, ECE A. · 2016 to 2020
$2.0MRole of Gut Bacterial Side-Chain Cleavage of Cortisol in Host 11Beta-Hydroxyandrostenedione FormationR01GM134423 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI RIDLON, JASON MICHAEL · 2020 to 2023
$1.3MStudies towards a pan-genome and genetic manipulation of Clostridium scindensR03AI147127 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI RIDLON, JASON MICHAEL · 2020 to 2021
$151kNCI NIH HHS R01 CA204808NCI NIH HHS R25 CA057699NCI NIH HHS T32 CA057699NIAID NIH HHS R03 AI147127NIGMS NIH HHS R01 GM134423NIGMS NIH HHS T32 GM140935NLM NIH HHS T15 LM007359
Abstract
The gut microbiome of vertebrates is capable of numerous biotransformations of bile acids, which are responsible for intestinal lipid digestion and function as key nutrient-signaling molecules. The human liver produces bile acids from cholesterol predominantly in the A/B-
Indexed as
Bile Acids and SaltsGastrointestinal MicrobiomeAnimalsBacillotaDeoxycholic AcidHumansLithocholic AcidPhylogenyBile Acids and SaltsDeoxycholic AcidLithocholic Acidbile acid 5α-reductasesbile acid dehydroxylationcolorectal cancerFirmicutesSecondary allo-bile acids
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.