Evidence map›Paper›PMID 36343496›Full record

ArticleEpidemics2022

The impact of reactive case detection on malaria transmission in Zanzibar in the presence of human mobility.

Aatreyee M Das, Manuel W Hetzel, Joshua O Yukich, Logan Stuck, Bakar S Fakih, Abdul-Wahid H Al-Mafazy, Abdullah Ali, Nakul Chitnis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epidemics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  8. Human mobility and the infectious disease transmission: A systematic review.Geo-spatial information science = Diqui kongjian xinxi kexue xuebao · 2024
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aatreyee M DasSwiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland. Electronic address: aatreyee.das@unibas.ch.
Manuel W HetzelSwiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland.
Joshua O YukichCenter for Applied Malaria Research and Evaluation, Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Logan StuckCenter for Applied Malaria Research and Evaluation, Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.
Bakar S FakihSwiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland; Ifakara Health Institute, Dar es Salaam, United Republic of Tanzania.
Abdul-Wahid H Al-MafazyZanzibar Malaria Elimination Programme, Zanzibar, United Republic of Tanzania.
Abdullah AliZanzibar Malaria Elimination Programme, Zanzibar, United Republic of Tanzania.
Nakul ChitnisSwiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland.

Funding

CDC HHS
6 · The paper itself

Abstract

Malaria persists at low levels on Zanzibar despite the use of vector control and case management. We use a metapopulation model to investigate the role of human mobility in malaria persistence on Zanzibar, and the impact of reactive case detection. The model was parameterized using survey data on malaria prevalence, reactive case detection, and travel history. We find that in the absence of imported cases from mainland Tanzania, malaria would likely cease to persist on Zanzibar. We also investigate potential intervention scenarios that may lead to elimination, especially through changes to reactive case detection. While we find that some additional cases are removed by reactive case detection, a large proportion of cases are missed due to many infections having a low parasite density that go undetected by rapid diagnostic tests, a low rate of those infected with malaria seeking treatment, and a low rate of follow up at the household level of malaria cases detected at health facilities. While improvements in reactive case detection would lead to a reduction in malaria prevalence, none of the intervention scenarios tested here were sufficient to reach elimination. Imported cases need to be treated to have a substantial impact on prevalence.

Indexed as

MalariaFamily CharacteristicsHumansPrevalenceSurveys and QuestionnairesTanzaniaHuman mobilityMalariaOrdinary differential equationsReactive case detectionSurveillance response systems

Identifiers

PMID36343496
PMCPMC9758615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.