Evidence map›Paper›PMID 36343353›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2023

Measurement of adherence to inhaled corticosteroids by self-report and electronic medication monitoring.

Ye Sun, Sunit Jariwala, Marina Reznik

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07224061 (Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination in Clinics and Schools), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07224061 narecruitingnot on this mapstarted 2026, after this paper: background citation

Promoting Asthma Guidelines and Management Through Technology-Based Intervention and Care Coordination in Clinics and Schools (PRAGMATIC-S)

TypeinterventionalSponsorMontefiore Medical CenterRan2026 to 2033Enrolled420ConditionsAsthma in ChildrenArmsPRAGMATIC-S
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. An Overview of Adherence-What It Is and Why It Is Important.The journal of allergy and clinical immunology. In practice · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ye SunDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-0609-4699
Sunit JariwalaDepartment of Medicine, Division of Allergy and Immunology, Montefiore Medical Center, Bronx, NY, USA.
Marina ReznikDepartment of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0001-7645-1260

Funding

CTSA Administrative Supplement for Informatics Core: A novel AI/ML system to predict respiratory failure and ARDS in Covid-19 patientsUL1TR002556 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, KIM, MIMI Y · 2018 to 2022
$26.7M
Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
NCATS NIH HHS UL1 TR001073NCATS NIH HHS UL1 TR002556
6 · The paper itself

Abstract

objectivePoor adherence to daily inhaled corticosteroids (ICS) is an important factor contributing to asthma morbidity. Assessing adherence in clinical settings using self-reported adherence often overestimates actual adherence. Electronic monitoring devices (EMDs) are objective means of assessing adherence, but are not routinely used in practice. Here, we aimed to establish adherence rates to ICS using EMDs in an inner-city, minority population in the Bronx, NY, and to compare two methods of self-reported adherence with EMD-measured adherence.

methodsPatients with physician-confirmed persistent asthma and daily ICS prescription were recruited. Self-reported adherence to ICS was measured by parental report for children and self-report for adults and the Medication Adherence Report Scale for Asthma (MARS-A). Two weeks after enrollment, EMD data were accessed for analysis. Daily adherence was calculated based on the number of puffs actuated per day as captured by EMD divided by the prescribed number of puffs.

results41 children and 40 adults participated. Median EMD-measured ICS adherence was 41% (children) and 43% (adults). This was significantly lower than the median self-reported adherence (100% for children,

conclusionsAdherence to daily ICS as measured using EMD is low in this population. In both adults and children, self-reported adherence was a poor indicator of true adherence. Further efforts using objective measures of medication adherence for patients with high asthma morbidity may be warranted to guide therapeutic decisions.

Indexed as

Anti-Asthmatic AgentsAsthmaAdministration, InhalationAdrenal Cortex HormonesAdultChildHumansMedication AdherenceSelf ReportAdrenal Cortex HormonesAnti-Asthmatic AgentsAdherenceasthmachildrenelectronic monitoringinhaled corticosteroids

Identifiers

PMID36343353
PMCPMC10191882

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.