ArticleAmerican journal of respiratory and critical care medicine2023
Pulmonary Arterial Hypertension Patients Have a Proinflammatory Gut Microbiome and Altered Circulating Microbial Metabolites.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
11.9field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Genetically determined gut microbiota associates with pulmonary arterial hypertension: a Mendelian randomization study.BMC pulmonary medicine · 2024Pooled it
- How gut microbiome and blood metabolites drive ossification of the posterior longitudinal ligament of the spine: a genome-wide association study based on the East Asian population.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Beyond the Heart-Lung Axis: A Review of the Crosstalk Between the Hemodynamic, Neurohormonal, and Immune Systems in Pulmonary Hypertension.Comprehensive physiology · 2026Review
- Axial Connectivity of the Lung Microbiome: A Review of Interorgan Crosstalk.Comprehensive physiology · 2026Review
- Review
- Gut microbiota-bile acid axis in cardiovascular disease: a spatiotemporal framework for predictive, preventive and personalised medicine.The EPMA journal · 2026Review
- Alterations in the fecal virome and bacteriome-virome interplay in IPAH.Respiratory research · 2026Article
- The bile acid-oxysterol axis in pulmonary arterial hypertension: from sterol trafficking to precision phenotyping and therapeutic opportunities.Molecular biology reports · 2026Review
- Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study.Comprehensive Physiology · 2026Article
- Endothelial-to-Mesenchymal Transition Mechanisms in Vascular Remodeling of Pulmonary Hypertension.International journal of molecular sciences · 2026Review
- Metabolomics of Right Ventricular Function in Pulmonary Hypertension.Circulation research · 2026Article
- Reduction in microbiota-derived short-chain fatty acids contributes to the pathogenesis of pulmonary arterial hypertension.Respiratory research · 2026Article
- Beyond the Vasculature: The Emerging Role of Systemic Metabolism and Immunometabolism in Pulmonary Arterial Hypertension.International journal of molecular sciences · 2026Review
- Paradigm shift: from pulmonary vasodilation to cardiopulmonary dual-track therapy-a comprehensive review of pathophysiology and advances in pulmonary hypertension-associated right heart failure.Respiratory research · 2026Review
- Morning Larks and Night Owls: Considering Chronotype in Evaluation of Patients with Pulmonary Hypertension.Annals of the American Thoracic Society · 2026Article
- Unveiling the gut-pancreas axis: microbial influence on stemness and tumor microenvironment of PDAC.Stem cells (Dayton, Ohio) · 2026Review
- Emerging insights of bile acids in cardiovascular physiology and disease: from molecular mechanisms to therapeutic potential.Frontiers in pharmacology · 2026Review
- Tryptophan metabolism: a potential link between the gut microbiota and pulmonary vascular remodeling in pulmonary hypertension.Frontiers in cellular and infection microbiology · 2026Review
- Alterations in gut microbiota and plasma metabolites in pulmonary arterial hypertension secondary to congenital left-to-right shunt heart disease: potential mechanisms and biomarkers.Frontiers in genetics · 2026Article
- Circadian clock-gut microbiota axis in pulmonary hypertension: linking gut-lung crosstalk, immune timing and vascular remodeling.Frontiers in physiology · 2026Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 2 countries.
Daphne M MoutsoglouDivision of Gastroenterology, Hepatology, and Nutrition.ORCID 0000-0002-4071-3756
Jasmine TatahDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0001-6414-2049
Sasha Z PriscoDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0002-9059-0635
Kurt W PrinsDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0002-0364-6742
Christopher StaleyDivision of Basic and Translational Research, Department of Surgery, and.ORCID 0000-0002-2309-0083
Sharon LopezDivision of Gastroenterology, Hepatology, and Nutrition.ORCID 0000-0002-1744-4447
Madelyn BlakeDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0002-6802-9470
Levi TeigenDivision of Gastroenterology, Hepatology, and Nutrition.ORCID 0000-0002-6409-0485
Felipe KazmirczakDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0001-8998-7259
E Kenneth WeirDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0002-6538-4143
Amanda J KabageDivision of Gastroenterology, Hepatology, and Nutrition.ORCID 0000-0003-3519-7416
Weihua GuanDivision of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-0956-9821
Alexander KhorutsDivision of Gastroenterology, Hepatology, and Nutrition.ORCID 0000-0002-3205-3188
Thenappan ThenappanDivision of Cardiovascular Medicine, Department of Medicine.ORCID 0000-0002-6210-0467
Translational Research Institute · AUUniversity of Minnesota · US
Funding
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9MGP130 Antagonism in Porcine RV Pressure OverloadR01HL162927 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$3.3MMulti-scale Investigation of Sex Differences in Right Ventricular Function via Estrogen-Microtubule InteractionsR01HL158795 · NHLBI · UNIVERSITY OF MINNESOTA · PI Kurt W Prins · 2022 to 2026
$2.8MTraining Program in Cardiac InnovationT32HL144472 · NHLBI · UNIVERSITY OF MINNESOTA · PI Peter A Crawford, SAMUEL C DUDLEY · 2019 to 2026
$2.6MMechanisms of Junctophilin-2 Misregulation that contribute to right ventricular dysfunction in pulmonary arterial hypertensionK08HL140100 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRINS, KURT W · 2018 to 2022
$785kInfluences of sex hormones on the microtubule cytoskeleton in right ventricular dysfunctionF32HL154533 · NHLBI · UNIVERSITY OF MINNESOTA · PI PRISCO, SASHA ZHENG · 2021 to 2021
$73kNCATS NIH HHS UL1 TR002494NHLBI NIH HHS F32 HL154533NHLBI NIH HHS K08 HL140100NHLBI NIH HHS R01 HL158795NHLBI NIH HHS R01 HL162927NHLBI NIH HHS T32 HL144472NIH HHS F32 HL154533NIH HHS T32 HL144472
Abstract
PubMed holds no abstract for this paper.
Indexed as
Gastrointestinal MicrobiomePulmonary Arterial HypertensionVascular DiseasesBile Acids and SaltsDysbiosisFamilial Primary Pulmonary HypertensionHumansInflammationPhylogenyBile Acids and Saltsdysbiosismetabolitesmicrobiomepulmonary arterial hypertension
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.