Evidence map›Paper›PMID 36343103›Full record

ReviewCirculation2022

Consumer-Led Screening for Atrial Fibrillation: Frontier Review of the AF-SCREEN International Collaboration.

Axel Brandes, Stavros Stavrakis, Ben Freedman, Sotiris Antoniou, Giuseppe Boriani, A John Camm, Clara K Chow, Eric Ding, Johan Engdahl, Michael M Gibson and 18 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Circulation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Inflammation and day-to-day occurrence of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Trial
  3. Systematic, randomized atrial fibrillation screening using detailed phenotyping with a risk prediction model combined with patch electrocardiogram in a Swedish population aged 65 years or older: the CONSIDERING-AF trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Trial
  4. Improving atrial fibrillation or flutter detection and management by smartphone-based photoplethysmography rhythm monitoring following cardiac surgery: a pragmatic randomized trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Trial
  5. Trial
  6. Review
  7. The weakest link in digital atrial fibrillation screening: a randomized comparison of self-applied ECG patch systems in older adults.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  8. Burden and age-specific trends of atrial fibrillation/atrial flutter from 1990 to 2023: a growing challenge among younger and middle-aged adults.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  9. Article
  10. Contemporary management of atrial fibrillation in patients with cancer-the 2025 European Heart Rhythm Association survey.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  11. Cost-effectiveness of atrial fibrillation screening programmes across European nations.European heart journal. Quality of care & clinical outcomes · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Screening and diagnosis of atrial fibrillation using wearable devices.The Korean journal of internal medicine · 2025
    Review
  19. Review
  20. Ethics of Wearable-Based Out-of-Hospital Cardiac Arrest Detection.Circulation. Arrhythmia and electrophysiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 11 countries.

Axel Brandes *Odense University Hospital, Denmark (A.B.).ORCID 0000-0001-9145-6887
Stavros Stavrakis *Cardiovascular Section, University of Oklahoma Health Science Center, Oklahoma City (S. Stavrakis).ORCID 0000-0002-4370-8135
Ben FreedmanHeart Research Institute (B.F.), University of Sydney, Australia.ORCID 0000-0002-3809-2911
Sotiris AntoniouBarts Health NHS Trust, London, United Kingdom (S.A.).ORCID 0000-0002-9149-1372
Giuseppe BorianiDepartment of Cardiology, University of Modena and Reggio Emilia, Italy (G.B.).ORCID 0000-0002-9820-4815
A John CammSt. George's University of London, United Kingdom (J.A.C.).ORCID 0000-0002-2536-2871
Clara K ChowCardiovascular Division (C.K.C.), University of Sydney, Australia.ORCID 0000-0003-4693-0038
Eric DingDepartment of Population and Quantitative Health Sciences (E.D.), University of Massachusetts Medical School, Worcester.ORCID 0000-0002-6904-8534
Johan EngdahlDepartment of Cardiology, Karolinska Institute, Stockholm, Sweden (J.E.).
Michael M GibsonBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (M.M.G.).
Gregory GolovchinerDepartment of Cardiology, Rabin Medical Center, Petah-Tivka, Israel (G.G.).
Taya GlotzerHackensack University Medical Center, NJ (T.G.).
Yutao GuoChinese PLA General Hospital, Beijing (Y.G.).ORCID 0000-0002-7626-7751
Jeff S HealeyCardiology Division, McMaster University, Hamilton, Canada (J.S.H.).ORCID 0000-0003-1216-7580
Mellanie T HillsStopAfib.org, Decatur, TX (M.T.H.).ORCID 0000-0001-8298-4418
Linda JohnsonLund University, Sweden (L.G.).ORCID 0000-0002-2249-8220
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool, United Kingdom (G.Y.H.L.).ORCID 0000-0002-7566-1626
Trudie LobbanArrhythmia Alliance, London, United Kingdom (T.L.).
Peter W MacfarlaneUniversity of Glasgow, United Kingdom (P.W.M.).ORCID 0000-0002-5390-1596
Gregory M MarcusDepartment of Cardiology, University of California, San Francisco (G.M.M.).ORCID 0000-0001-5197-7696
David D McManusDepartment of Medicine (D.D.M.), University of Massachusetts Medical School, Worcester.
Lis NeubeckCentre for Cardiovascular Health, Edinburgh Napier University, United Kingdom (L.N.).
Jessica OrchardCharles Perkins Centre, University of Sydney, Australia (J.O.).ORCID 0000-0002-5702-7277
Marco V PerezStanford University Medical Center, Palo Alto, CA (M.V.P., M.P.T.).ORCID 0000-0003-2746-0202
Renate B SchnabelUniversity Heart & Vascular Center Hamburg Eppendorf, Germany (R.B.S.).ORCID 0000-0001-7170-9509
Breda SmythDepartment of Public Health, Health Service Executive West, Galway, Ireland (B.S.).
Steven SteinhublScripps Research Translational Institute, La Jolla, CA (S. Steinhubl).ORCID 0000-0002-9256-7914
Mintu P TurakhiaStanford University Medical Center, Palo Alto, CA (M.V.P., M.P.T.).ORCID 0000-0001-8025-0904
Twitter (United States) · USUniversity of Massachusetts Chan Medical School · USBarts Health NHS Trust · GBBeth Israel Deaconess Medical Center · USCharles Sturt University · AUChinese PLA General Hospital · CNEdinburgh Napier University · GBHackensack University Medical Center · USHealth Service Executive · IEKarolinska Institutet · SELund University · SEMcMaster University · CAOdense University Hospital · DKRabin Medical Center · ILScripps Research Institute · USSt George's, University of London · GBSt. Gregory's University · USThe Arrhythmia Institute · USThe Heart Research Institute · AUThe University of Sydney · AU

Funding

Addressing Health Disparities among Oklahoma Minority and Rural Communities through Clinical Research Education and Career DevelopmentR25MD011564 · NIMHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HOUCHEN, COURTNEY WAYNE, STAVRAKIS, STAVROS · 2017 to 2021
$2.7M
Biomarker-guided optimization of transcutaneous vagal stimulation for atrial fibrillationR01HL161008 · NHLBI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Stavros Stavrakis · 2022 to 2026
$1.9M
NHLBI NIH HHS R01 HL161008NIMHD NIH HHS R25 MD011564
6 · The paper itself

Abstract

The technological evolution and widespread availability of wearables and handheld ECG devices capable of screening for atrial fibrillation (AF), and their promotion directly to consumers, has focused attention of health care professionals and patient organizations on consumer-led AF screening. In this Frontiers review, members of the AF-SCREEN International Collaboration provide a critical appraisal of this rapidly evolving field to increase awareness of the complexities and uncertainties surrounding consumer-led AF screening. Although there are numerous commercially available devices directly marketed to consumers for AF monitoring and identification of unrecognized AF, health care professional-led randomized controlled studies using multiple ECG recordings or continuous ECG monitoring to detect AF have failed to demonstrate a significant reduction in stroke. Although it remains uncertain if consumer-led AF screening reduces stroke, it could increase early diagnosis of AF and facilitate an integrated approach, including appropriate anticoagulation, rate or rhythm management, and risk factor modification to reduce complications. Companies marketing AF screening devices should report the accuracy and performance of their products in high- and low-risk populations and avoid claims about clinical outcomes unless improvement is demonstrated in randomized clinical trials. Generally, the diagnostic yield of AF screening increases with the number, duration, and temporal dispersion of screening sessions, but the prognostic importance may be less than for AF detected by single-time point screening, which is largely permanent, persistent, or high-burden paroxysmal AF. Consumer-initiated ECG recordings suggesting possible AF always require confirmation by a health care professional experienced in ECG reading, whereas suspicion of AF on the basis of photoplethysmography must be confirmed with an ECG. Consumer-led AF screening is unlikely to be cost-effective for stroke prevention in the predominantly young, early adopters of this technology. Studies in older people at higher stroke risk are required to demonstrate both effectiveness and cost-effectiveness. The direct interaction between companies and consumers creates new regulatory gaps in relation to data privacy and the registration of consumer apps and devices. Although several barriers for optimal use of consumer-led screening exist, results of large, ongoing trials, powered to detect clinical outcomes, are required before health care professionals should support widespread adoption of consumer-led AF screening.

Indexed as

Atrial FibrillationStrokeAgedElectrocardiographyHumansMass ScreeningRisk Factorsatrial fibrillationscreeningwearable electronic devices

Identifiers

PMID36343103
PMCPMC9673231
OpenAlexW4308410008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.