Evidence map›Paper›PMID 36342940›Full record

Trial reportPloS one2022

Effect of a one-time financial incentive on linkage to chronic hypertension care in Kenya and Uganda: A randomized controlled trial.

Matthew D Hickey, Asiphas Owaraganise, Norton Sang, Fredrick J Opel, Erick Wafula Mugoma, James Ayieko, Jane Kabami, Gabriel Chamie, Elijah Kakande, Maya L Petersen and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04810650 (A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04810650 nacompletednot on this map

A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East Africa

TypeinterventionalSponsorUniversity of California, San FranciscoRan2021 to 2023Enrolled2,233ConditionsHIV, Hypertension, Alcohol Drinking, Maternal Child HealthArmsMobility Dynamic Treatment Intervention, Health Living Intervention for Heavy Alcohol Users, Hypertension Linkage, PrEP/PEP at Outpatient Clinics, PrEP/PEP at Antenatal Clinics
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Matthew D HickeyDivision of HIV, Infectious Disease, & Global Medicine, University of California, San Francisco, CA, United States of America.ORCID 0000-0001-8913-1602
Asiphas OwaraganiseInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0002-5594-0310
Norton SangKenya Medical Research Institute, Nairobi, Kenya.
Fredrick J OpelKenya Medical Research Institute, Nairobi, Kenya.
Erick Wafula MugomaKenya Medical Research Institute, Nairobi, Kenya.
James AyiekoKenya Medical Research Institute, Nairobi, Kenya.
Jane KabamiInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0002-0265-3174
Gabriel ChamieDivision of HIV, Infectious Disease, & Global Medicine, University of California, San Francisco, CA, United States of America.
Elijah KakandeInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0001-9532-5710
Maya L PetersenSchool of Public Health, University of California, Berkeley, CA, United States of America.
Laura B BalzerSchool of Public Health, University of California, Berkeley, CA, United States of America.ORCID 0000-0002-3730-410X
Moses R KamyaInfectious Diseases Research Collaboration, Kampala, Uganda.
Diane V HavlirDivision of HIV, Infectious Disease, & Global Medicine, University of California, San Francisco, CA, United States of America.
Infectious Diseases Research Collaboration · UGKenya Medical Research Institute · KEUniversity of California, San Francisco · USUniversity of California, Berkeley · US

Funding

A Multisectoral Strategy to Address Persistent Drivers of the HIV Epidemic in East AfricaU01AI150510 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V, KAMYA, MOSES ROBERT · 2020 to 2025
$23.4M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Implementation Strategies to Improve Hypertension Treatment in KenyaK23HL162578 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Matthew Hickey · 2022 to 2026
$944k
NHLBI NIH HHS K23 HL162578NIAID NIH HHS T32 AI060530NIAID NIH HHS U01 AI150510
6 · The paper itself

Abstract

backgroundFewer than 10% of people with hypertension in sub-Saharan Africa are diagnosed, linked to care, and achieve hypertension control. We hypothesized that a one-time financial incentive and phone call reminder for missed appointments would increase linkage to hypertension care following community-based screening in rural Uganda and Kenya.

methodsIn a randomized controlled trial, we conducted community-based hypertension screening and enrolled adults ≥25 years with blood pressure ≥140/90 mmHg on three measures; we excluded participants with known hypertension or hypertensive emergency. The intervention was transportation reimbursement upon linkage (~$5 USD) and up to three reminder phone calls for those not linking within seven days. Control participants received a clinic referral only. Outcomes were linkage to hypertension care within 30 days (primary) and hypertension control <140/90 mmHg measured in all participants at 90 days (secondary). We used targeted minimum loss-based estimation to compute adjusted risk ratios (aRR).

resultsWe screened 1,998 participants, identifying 370 (18.5%) with uncontrolled hypertension and enrolling 199 (100 control, 99 intervention). Reasons for non-enrollment included prior hypertension diagnosis (n = 108) and hypertensive emergency (n = 32). Participants were 60% female, median age 56 (range 27-99); 10% were HIV-positive and 42% had baseline blood pressure ≥160/100 mmHg. Linkage to care within 30 days was 96% in intervention and 66% in control (aRR 1.45, 95%CI 1.25-1.68). Hypertension control at 90 days was 51% intervention and 41% control (aRR 1.22, 95%CI 0.92-1.66).

conclusionA one-time financial incentive and reminder call for missed visits resulted in a 30% absolute increase in linkage to hypertension care following community-based screening. Financial incentives can improve the critical step of linkage to care for people newly diagnosed with hypertension in the community.

Indexed as

HIV InfectionsHypertensionAdultFemaleHumansKenyaMaleMiddle AgedMotivationUganda

Identifiers

PMID36342940
PMCPMC9639834
OpenAlexW4308411489

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.