Evidence map›Paper›PMID 36342640›Full record

ArticleRadiological physics and technology2023

Deep learning model for breast cancer diagnosis based on bilateral asymmetrical detection (BilAD) in digital breast tomosynthesis images.

Daiki Shimokawa, Kengo Takahashi, Daiya Kurosawa, Eichi Takaya, Ken Oba, Kazuyo Yagishita, Toshinori Fukuda, Hiroko Tsunoda, Takuya Ueda

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Article in Radiological physics and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Daiki ShimokawaDepartment of Clinical Imaging, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, Miyagi, 980-8575, Japan.
Kengo TakahashiDepartment of Clinical Imaging, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, Miyagi, 980-8575, Japan.
Daiya KurosawaDepartment of Clinical Imaging, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, Miyagi, 980-8575, Japan.
Eichi TakayaAI Lab, Tohoku University Hospital, 1-1 Seiryo-Machi, Aoba-Ku, Sendai, Miyagi, 980-8574, Japan.
Ken ObaDepartment of Radiology, St. Luke's International Hospital, 9-1, Akashi-Cho, Chuo-Ku, Tokyo, Tokyo, 104-8560, Japan.
Kazuyo YagishitaDepartment of Radiology, St. Luke's International Hospital, 9-1, Akashi-Cho, Chuo-Ku, Tokyo, Tokyo, 104-8560, Japan.
Toshinori FukudaDepartment of Radiology, St. Luke's International Hospital, 9-1, Akashi-Cho, Chuo-Ku, Tokyo, Tokyo, 104-8560, Japan.
Hiroko TsunodaDepartment of Radiology, St. Luke's International Hospital, 9-1, Akashi-Cho, Chuo-Ku, Tokyo, Tokyo, 104-8560, Japan.
Takuya UedaDepartment of Clinical Imaging, Tohoku University Graduate School of Medicine, 2-1 Seiryo-Machi, Aoba-Ku, Sendai, Miyagi, 980-8575, Japan. takuya.ueda.d3@tohoku.ac.jp.ORCID http://orcid.org/0000-0002-0913-5791

Funding

Core Research for Evolutional Science and Technology JPMJCR15D1
6 · The paper itself

Abstract

The purpose of this study was to develop a deep learning model to diagnose breast cancer by embedding a diagnostic algorithm that examines the asymmetry of bilateral breast tissue. This retrospective study was approved by the institutional review board. A total of 115 patients who underwent breast surgery and had pathologically confirmed breast cancer were enrolled in this study. Two image pairs [230 pairs of bilateral breast digital breast tomosynthesis (DBT) images with 115 malignant tumors and contralateral tissue (M/N), and 115 bilateral normal areas (N/N)] were generated from each patient enrolled in this study. The proposed deep learning model is called bilateral asymmetrical detection (BilAD), which is a modified convolutional neural network (CNN) model of Xception with two-dimensional tensors for bilateral breast images. BilAD was trained to classify the differences between pairs of M/N and N/N datasets. The results of the BilAD model were compared to those of the unilateral control CNN model (uCNN). The results of BilAD and the uCNN were as follows: accuracy, 0.84 and 0.75; sensitivity, 0.73 and 0.58; and specificity, 0.93 and 0.92, respectively. The mean area under the receiver operating characteristic curve of BilAD was significantly higher than that of the uCNN (p = 0.02): 0.90 and 0.84, respectively. The proposed deep learning model trained by embedding a diagnostic algorithm to examine the asymmetry of bilateral breast tissue improves the diagnostic accuracy for breast cancer.

Indexed as

Breast NeoplasmsDeep LearningBreastFemaleHumansMammographyRetrospective StudiesArtificial intelligenceBreast cancerDeep learningDigital breast tomosynthesisMammography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.