Evidence map›Paper›PMID 36342637›Full record

Observational studyJournal of thrombosis and thrombolysis2023

A multicentre observational study of the prevalence, management, and outcomes of subsegmental pulmonary embolism.

Michael N Armitage, Aishah Z Mughal, Christopher C Huntley, Daniel Lasserson, Michael Newnham

Erratum issuedOpen access · hybridAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Journal of thrombosis and thrombolysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Michael N ArmitageUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom.
Aishah Z MughalUniversity of Birmingham, Birmingham, United Kingdom.
Christopher C HuntleyOccupational and Interstitial Lung Disease Services, Institute of Applied Health Research, University Hospitals Birmingham NHS Foundation Trust, University of Birmingham, Birmingham, United Kingdom.
Daniel LassersonUniversity of Warwick, Coventry, United Kingdom.
Michael NewnhamOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom. michaelnewnham@nhs.net.
University of Birmingham · GBOxford University Hospitals NHS Trust · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of subsegmental pulmonary embolism (SSPE) has increased with improvements in imaging technology. There is clinical equipoise for SSPE treatment, with conflicting evidence of improved mortality or reduced venous thromboembolism recurrence with anticoagulation. SSPE studies have significant heterogeneity and often lack adequately matched disease comparator groups.

objectivesTo determine the prevalence, management, and outcomes of SSPE and compare them to patients with main, lobar, segmental, and no pulmonary embolism (PE). PATIENTS/

methodsAll adult patients undergoing CT pulmonary angiography (CTPA) between 2013 and 2019, at 3 UK hospitals were included in the study. CTPA reports were text mined for language relating to PE, and then further manually screened for the presence and anatomical location of PE. Patient groups were propensity matched by age, sex, and year of CTPA prior to analysis. 3-month outcomes of major bleeding, VTE recurrence, and death were recorded.

results79 (3.8%) SSPEs were identified from 2,055 diagnoses of PE, and 14,300 CTPA reports. 44 (56%) of SSPEs were single artery emboli, 25 (32%) were multiple unilateral emboli, and 10 (13%) were multiple bilateral emboli. Mortality, VTE recurrence and major bleeding were similar at 3 months across all groups. 87.3% of SSPE imaging reports had an additional radiological diagnosis, with pleural effusion (30%), consolidation (19%), and cardiomegaly (19%) being the most common.

conclusionThe prevalence of SSPE was 3.8% of all PEs and there were a substantial number of additional radiological findings in the SSPE group that may have accounted for their symptoms.

Indexed as

Pulmonary EmbolismSubacute Sclerosing PanencephalitisVenous ThromboembolismAdultAnticoagulantsHemorrhageHumansPrevalenceAnticoagulantsAnticoagulantsEmbolismPrevalencePulmonary embolismVenous thromboembolism

Identifiers

PMID36342637
PMCPMC9925472
OpenAlexW4308368851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.