Evidence map›Paper›PMID 36342031›Full record

ArticleCardiology journal2023

Long-term clinical outcomes in patients with acute myocardial infarction complicated by cardiogenic shock according to the application and initiation time of extracorporeal membrane oxygenation in South Korea.

Dae Young Hyun, Xiongyi Han, Seok Oh, Joon Ho Ahn, Seung Hun Lee, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Dae Young HyunDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea. m-dragon1@hanmail.net.
Xiongyi HanDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Seok OhDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Joon Ho AhnDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Seung Hun LeeDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Kyung Hoon ChoDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Min Chul KimDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Doo Sun SimDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Young Joon HongDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Ju Han KimDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Youngkeun AhnDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Myung Ho JeongDepartment of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.
Chonnam National University Hospital · KRChonnam National University Hwasun Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited data are available regarding the proper application time and long-term outcomes of extracorporeal membrane oxygenation (ECMO) in patients with cardiogenic shock. This cohort study appraised the clinical outcomes according to ECMO application without or before cardiopulmonary resuscitation (CPR) in patients with acute myocardial infarction (AMI) combined with cardiogenic shock.

methodsBetween 2011 and 2015, a total of 13,104 patients with AMI were enrolled in a nationwide AMI registry. Eligible patients with cardiogenic shock, who underwent percutaneous coronary intervention, with a 3-year clinical follow-up, were analyzed. The 949 included patients were divided into two groups: no ECMO (n = 845) and ECMO application (n = 104). The ECMO group was further divided into ECMO without or before CPR (n = 11) and ECMO after CPR (n = 93).

resultsSignificant differences were noted in major adverse cardiac events (MACEs) between the no ECMO and ECMO application groups during the 3-year follow-up (41.5% vs. 80.8%; p < 0.001). However, the ECMO without or before CPR group showed similar outcomes to the no ECMO group in 3-year MACEs (63.6% vs. 41.5%; p = 0.055). MACEs during 3 years of follow-up were significantly lower in the ECMO without or before CPR group than in the ECMO after CPR group (63.6% vs. 82.8%; p = 0.005).

conclusionsA significantly lower risk of major cardiac events in ECMO without or before CPR suggests that early application of ECMO can be a reasonable strategy to improve outcomes in patients with AMI complicated by cardiogenic shock.

Indexed as

Extracorporeal Membrane OxygenationMyocardial InfarctionCohort StudiesHumansRepublic of KoreaRetrospective StudiesShock, Cardiogeniccardiogenic shockcardiopulmonary resuscitationextracorporeal membrane oxygenationmyocardial infarctionpercutaneous coronary intervention

Identifiers

PMID36342031
PMCPMC10635714
OpenAlexW4308365399

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.