Evidence map›Paper›PMID 36341514›Full record

ReviewDiabetes & vascular disease research

Glycaemic variability and risk of adverse cardiovascular events in acute coronary syndrome.

Lei Zhang, Feng Li, Huan-Huan Liu, Zhi-Yuan Zhang, Fan Yang, Ling-Ling Qian, Ru-Xing Wang

Open access · diamondAbstract readReview
In one paragraph

Review in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei ZhangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.ORCID 0000-0003-1186-8852
Feng LiDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Huan-Huan LiuWuxi School of Medicine, Jiangnan University, Wuxi, China.
Zhi-Yuan ZhangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Fan YangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Ling-Ling QianDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Ru-Xing WangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.ORCID 0000-0001-7355-5048
Wuxi People's Hospital · CNJiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe relationship between different glycaemic variability (GV) indexes and adverse cardiovascular outcomes is not well understood. This study aims to determine whether GV is related to the occurrence of adverse cardiovascular events in patients with acute coronary syndrome (ACS).

methodsPubMed, EMBASE, and Web of Science were comprehensively searched from the establishment of databases to 29 June 2022. The relationship between two important GV indexes, including the mean amplitude of glycemic excursion (MAGE) and standard deviation (SD), and the adverse cardiovascular events in ACS patients were evaluated, respectively.

resultsA total of 11 studies with 3709 ACS patients were included. Pooled results showed that patients with higher GV had significantly increased risk of adverse cardiovascular events, including MAGE (relative risk [RR] = 1.76, 95% CI: 1.40 to 2.22,

conclusionsIncreased GV is related to the poor prognosis in patients with ACS. Additionally, more well-designed studies comparing different indicators of GV with adverse cardiovascular events in ACS patients are still warranted.

Indexed as

Acute Coronary SyndromeHyperglycemiaBlood GlucoseHumansBlood Glucoseacute coronary syndromeadverse cardiovascular eventsGlycaemic variabilitymeta-analysis

Identifiers

PMID36341514
PMCPMC9643761
OpenAlexW4308496122

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.