Evidence map›Paper›PMID 36341441›Full record

ArticleFrontiers in immunology2022

The beneficial effects of

Stphannie Jamyla de Araújo Barbosa, Maisie Mitchele Barbosa Oliveira, Susana Barbosa Ribeiro, Caroline Addison Carvalho Xavier de Medeiros, Maria Laura de Souza Lima, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Júnior, Francisco Caninde de Sousa Junior, Agnes Andrade Martins, Daniel Felipe Fernandes Paiva and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

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  3. Trending ileal microbiome dysbiosis over time as an early assessment of intestinal transplant rejection risk.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Stphannie Jamyla de Araújo BarbosaPostgraduate Program in Pharmaceutical Science, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Maisie Mitchele Barbosa OliveiraPostgraduate Program in Biotechnology /RENORBIO, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Susana Barbosa RibeiroDepartment of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Caroline Addison Carvalho Xavier de MedeirosPostgraduate Program in Biotechnology /RENORBIO, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Maria Laura de Souza LimaPostgraduate Program in Oral Sciences, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Gerlane Coelho Bernardo GuerraPostgraduate Program in Pharmaceutical Science, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Raimundo Fernandes de Araújo JúniorPostgraduate Program in Health Sciences, Department of Morphology, Federal University of Rio Grande Norte, Natal, Brazil.
Francisco Caninde de Sousa JuniorPostgraduate Program in Pharmaceutical Science, Department of Pharmaceutical Science, Federal University of Rio Grande Norte, Natal, Brazil.
Agnes Andrade MartinsDepartment of Dentistry, Federal University of Rio Grande Norte, Natal, Brazil.
Daniel Felipe Fernandes PaivaDepartment of Dentistry, Federal University of Rio Grande Norte, Natal, Brazil.
Raphael Victor Silva AndradeDepartment of Dentistry, Federal University of Rio Grande Norte, Natal, Brazil.
Conceição S Martins RebouçasDepartment of Morphology, Federal University of Ceará, Fortaleza, Brazil.
Gerly Anne de Castro BritoDepartment of Morphology, Federal University of Ceará, Fortaleza, Brazil.
Renata Ferreira de Carvalho LeitâoDepartment of Morphology, Federal University of Ceará, Fortaleza, Brazil.
Aurigena Antunes de AraújoPostgraduate Program in Pharmaceutical Science, Department of Biophysical and Pharmacology, Federal University of Rio Grande Norte, Natal, Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade Federal do Rio Grande · BRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intestinal mucositis is one of the most common and important side effects of 5-fluorouracil (5-FU). Currently, there are still no specific and effective protocols for its prevention and treatment. The aim of the present study was to evaluate the effect of oral administration of Lacticaseibacillus casei ( Results: The positive impact of Conclusion: Oral

Indexed as

Lacticaseibacillus caseiMucositisAnimalsColonFluorouracilInterleukin-6Intestinal MucosaIntestine, SmallMiceOccludinToll-Like Receptor 4Tumor Necrosis Factor-alphaFluorouracilInterleukin-6OccludinToll-Like Receptor 4Tumor Necrosis Factor-alpha5-fluorouracilchemotherapyLacticaseibacillus caseimucositisprobiotic

Identifiers

PMID36341441
PMCPMC9635922
OpenAlexW4307166226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.