Evidence map›Paper›PMID 36341427›Full record

ArticleFrontiers in immunology2022

Association of smoking status with non-small cell lung cancer patients harboring uncommon epidermal growth factor receptor mutation.

How-Wen Ko, Shian-Sen Shie, Chih-Wei Wang, Chi-Tsun Chiu, Chih-Liang Wang, Tsung-Ying Yang, Shou-Chu Chou, Chien-Ying Liu, Chih-Hsi Scott Kuo, Yu-Ching Lin and 3 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Spectrum of rareNarra J · 2025
    Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. A Functional Genomics Review of Non-Small-Cell Lung Cancer in Never Smokers.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

How-Wen KoDivision of Thoracic Oncology, Department of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Shian-Sen ShieDepartment of Internal Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chih-Wei WangDepartment of Pathology, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chi-Tsun ChiuInstitute of European and American Studies, Academia Sinica, Taipei, Taiwan.
Chih-Liang WangDivision of Thoracic Oncology, Department of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tsung-Ying YangDivision of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Shou-Chu ChouDepartment of Family Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei, Taiwan.
Chien-Ying LiuDivision of Thoracic Oncology, Department of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chih-Hsi Scott KuoDivision of Thoracic Oncology, Department of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yu-Ching LinDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Puzi, Taiwan.
Li-Fu LiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Keelung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Keelung, Taiwan.
Cheng-Ta YangDivision of Thoracic Oncology, Department of Thoracic Medicine, Linkou Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Chin-Chou WangDivisions of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Uncommon epidermal growth factor receptor (EGFR) mutations include single and complex mutations. However, the association of the smoking status of patients with uncommon and complex Methods: This retrospective study evaluates the spectrum of uncommon Results: Between 2010 and 2019, 5,608 non-small cell lung cancer (NSCLC) patients were analyzed. Conclusions: Our study demonstrates not only a comprehensive spectrum of uncommon

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsErbB ReceptorsHumansMutationProtein Kinase InhibitorsRetrospective StudiesSmokingErbB ReceptorsProtein Kinase Inhibitorscomplex EGFR mutationepidermal growth factor receptor (EGFR)non-small cell lung cancer (NSCLC)smokinguncommon EGFR mutation

Identifiers

PMID36341427
PMCPMC9632177

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.