Evidence map›Paper›PMID 36341408›Full record

ArticleFrontiers in immunology2022

The protective role of caffeic acid on bovine mammary epithelial cells and the inhibition of growth and biofilm formation of Gram-negative bacteria isolated from clinical mastitis milk.

Tianle Xu, Hao Zhu, Run Liu, Xinyue Wu, Guangjun Chang, Yi Yang, Zhangping Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Antibacterial properties ofFrontiers in pharmacology · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tianle XuJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou, China.
Hao ZhuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Run LiuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Xinyue WuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Guangjun ChangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Yi YangCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhangping YangJoint International Research Laboratory of Agriculture and Agri-Product Safety, Ministry of Education of China, Yangzhou University, Yangzhou, China.
Yangzhou University · CNNanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a first-line barrier against bacterial infection of mammary tissues, bovine mammary epithelial cells (bMECs) are generally believed to be involved in the immune response due to exogenous stress. Due to the escalating crisis of antibiotic resistance, there is an urgent need for new strategies to combat pathogenic bacteria-infected bovine mastitis. In this study, isolated bMECs and Institute of Cancer Research (ICR) mice were used for

Indexed as

Mastitis, BovineMilkAnimalsBacteriaBiofilmsCaffeic AcidsCattleEpithelial CellsEscherichia coliFemaleGram-Negative BacteriaHumansMicecaffeic acidCaffeic Acidsanti-inflammatory activityantimicrobialbovine mastitiscaffeic acidgram-negative bacteria

Identifiers

PMID36341408
PMCPMC9632277
OpenAlexW4306874805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.