Evidence map›Paper›PMID 36341350›Full record

Observational studyFrontiers in immunology2022

Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies.

Christian P Moritz, Le-Duy Do, Yannick Tholance, Pierre-Baptiste Vallayer, Véronique Rogemond, Bastien Joubert, Karine Ferraud, Coralie La Marca, Jean-Philippe Camdessanché, Jérôme Honnorat and 1 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Inter-Laboratory Validation of Nodal/Paranodal Antibody Testing.Journal of the peripheral nervous system : JPNS · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Anti-AGO1 Antibodies Identify a Subset of Autoimmune Sensory Neuronopathy.Neurology(R) neuroimmunology & neuroinflammation · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Christian P MoritzDepartment of Neurology, University hospital of Saint-Etienne, Saint-Etienne, France.
Le-Duy DoSynaptopathies and autoantibodies (SynatAc) team, Mechanisms In Integrated Life Sciences (MELIS) Laboratory, Institute NeuroMyoGène (INMG), INSERM U1314/CNRS UMR 5284, Universités de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Yannick TholanceSynaptopathies and autoantibodies (SynatAc) team, Mechanisms In Integrated Life Sciences (MELIS) Laboratory, Institute NeuroMyoGène (INMG), INSERM U1314/CNRS UMR 5284, Universités de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Pierre-Baptiste VallayerDepartment of Neurology, University hospital of Saint-Etienne, Saint-Etienne, France.
Véronique RogemondSynaptopathies and autoantibodies (SynatAc) team, Mechanisms In Integrated Life Sciences (MELIS) Laboratory, Institute NeuroMyoGène (INMG), INSERM U1314/CNRS UMR 5284, Universités de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Bastien JoubertSynaptopathies and autoantibodies (SynatAc) team, Mechanisms In Integrated Life Sciences (MELIS) Laboratory, Institute NeuroMyoGène (INMG), INSERM U1314/CNRS UMR 5284, Universités de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Karine FerraudDepartment of Neurology, University hospital of Saint-Etienne, Saint-Etienne, France.
Coralie La MarcaSynaptopathies and autoantibodies (SynatAc) team, Mechanisms In Integrated Life Sciences (MELIS) Laboratory, Institute NeuroMyoGène (INMG), INSERM U1314/CNRS UMR 5284, Universités de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Jean-Philippe CamdessanchéDepartment of Neurology, University hospital of Saint-Etienne, Saint-Etienne, France.
Jérôme HonnoratSynaptopathies and autoantibodies (SynatAc) team, Mechanisms In Integrated Life Sciences (MELIS) Laboratory, Institute NeuroMyoGène (INMG), INSERM U1314/CNRS UMR 5284, Universités de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Jean-Christophe AntoineDepartment of Neurology, University hospital of Saint-Etienne, Saint-Etienne, France.
Université Claude Bernard Lyon 1 · FRCentre Hospitalier Universitaire de Saint-Étienne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoantibodies (Abs) are biomarkers for many disease conditions and are increasingly used to facilitate diagnosis and treatment decisions. To guarantee high sensitivity and specificity, the choice of their detection method is crucial.

Indexed as

AutoantibodiesAutoimmune DiseasesEnzyme-Linked Immunosorbent AssayEpitopesHumansImmunoglobulin GAutoantibodiesEpitopesImmunoglobulin GAnti-Su antibodiesargonaute antibodiesautoimmune neuropathyconformation-stabilizing ELISAganglionopathiesensory neuronopathy

Identifiers

PMID36341350
PMCPMC9630334
OpenAlexW4306948604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.