Evidence map›Paper›PMID 36341341›Full record

ArticleFrontiers in immunology2022

IκBNS expression in B cells is dispensable for IgG responses to T cell-dependent antigens.

Sharesta Khoenkhoen, Monika Ádori, Darío Solís-Sayago, Juliette Soulier, Jamie Russell, Bruce Beutler, Gabriel K Pedersen, Gunilla B Karlsson Hedestam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Regulation and Function of the Atypical IκBs-Bcl-3, IκBEuropean journal of immunology · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Sharesta KhoenkhoenDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Monika ÁdoriDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Darío Solís-SayagoDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Juliette SoulierDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Jamie RussellCenter for the Genetics of Host Defense, University of Texas (UT) Southwestern Medical Center, Dallas, TX, United States.
Bruce BeutlerCenter for the Genetics of Host Defense, University of Texas (UT) Southwestern Medical Center, Dallas, TX, United States.
Gabriel K PedersenCenter for Vaccine Research, Statens Serum Institut, Copenhagen, Denmark.
Gunilla B Karlsson HedestamDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SESouthwestern Medical CenterStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mice lacking the atypical inhibitory kappa B (IκB) protein, IκBNS, a regulator of the NF-κB pathway encoded by the

Indexed as

AntigensB-LymphocytesAnimalsCell DifferentiationImmunoglobulin GMiceMice, KnockoutNF-kappa BAntigensImmunoglobulin GNF-kappa BB cell responsesCD79aconditionalIκBNSnfkbidNF-κB

Identifiers

PMID36341341
PMCPMC9634154
OpenAlexW4306968949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.