Evidence map›Paper›PMID 36341337›Full record

ArticleFrontiers in immunology2022

Human placental hematopoietic stem cell-derived natural killer cells (CYNK) recognize and eliminate influenza A virus-infected cells.

Manojkumar Gunasekaran, Andrea Difiglia, John Fitzgerald, Robert Hariri, William van der Touw, Tanel Mahlakõiv

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Manojkumar GunasekaranCelularity Inc., Florham Park, NJ, United States.
Andrea DifigliaCelularity Inc., Florham Park, NJ, United States.
John FitzgeraldCelularity Inc., Florham Park, NJ, United States.
Robert HaririCelularity Inc., Florham Park, NJ, United States.
William van der TouwCelularity Inc., Florham Park, NJ, United States.
Tanel MahlakõivCelularity Inc., Florham Park, NJ, United States.
Celularity (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus (IAV) infections are a significant recurrent threat to public health and a significant burden on global economy, highlighting the need for developing more effective therapies. Natural killer (NK) cells play a pivotal role in the control of pulmonary IAV infection, however, little is known about the therapeutic potential of adoptively transferred NK cells for viral infections. Here, we investigated the antiviral activity of CYNK, human placental hematopoietic stem cell-derived NK cells, against IAV infection

Indexed as

Influenza A virusInfluenza, HumanAntiviral AgentsFemaleHematopoietic Stem CellsHumansKiller Cells, NaturalPlacentaPregnancyAntiviral Agentsantiviralcell therapyimmunotherapyinfluenzaNK cellsvirus

Identifiers

PMID36341337
PMCPMC9632418
OpenAlexW4306879422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.