Evidence map›Paper›PMID 36341331›Full record

ReviewFrontiers in immunology2022

PET/CT molecular imaging in the era of immune-checkpoint inhibitors therapy.

Yuan Gao, Caixia Wu, Xueqi Chen, Linlin Ma, Xi Zhang, Jinzhi Chen, Xuhe Liao, Meng Liu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Optimizing acquisition time and injected dose inBMC medical informatics and decision making · 2026
    Article
  5. Review
  6. Imaging Immunotherapy.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  7. Review
  8. Assessment of tertiary lymphoid structures viaCancer immunology, immunotherapy : CII · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Targeting of immune checkpoint regulator V-domain Ig suppressor of T-cell activation (VISTA) withEuropean journal of nuclear medicine and molecular imaging · 2024
    Article
  14. IsCancers · 2024
    Review
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yuan GaoDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Caixia WuDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Xueqi ChenDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Linlin MaDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Xi ZhangDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Jinzhi ChenDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Xuhe LiaoDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Meng LiuDepartment of Nuclear Medicine, Peking University First Hospital, Beijing, China.
Peking University · CNPeking University First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer immunotherapy, especially immune-checkpoint inhibitors (ICIs), has paved a new way for the treatment of many types of malignancies, particularly advanced-stage cancers. Accumulating evidence suggests that as a molecular imaging modality, positron emission tomography/computed tomography (PET/CT) can play a vital role in the management of ICIs therapy by using different molecular probes and metabolic parameters. In this review, we will provide a comprehensive overview of the clinical data to support the importance of

Indexed as

NeoplasmsPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18HumansImmune Checkpoint InhibitorsMolecular ImagingMolecular ProbesTumor MicroenvironmentFluorodeoxyglucose F18Immune Checkpoint InhibitorsMolecular Probesimmune-checkpoint inhibitors (ICIs)metabolic parametermolecular imagingmolecular probepositron emission tomography/computed tomography (PET/CT)tumor microenvironment (TME)

Identifiers

PMID36341331
PMCPMC9630646
OpenAlexW4306930167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.