Evidence map›Paper›PMID 36341284›Full record

ArticleNanoscale advances2022

Nanovector-mediated exogenous delivery of dsRNA induces silencing of target genes in very young tomato flower buds.

B Molesini, F Pennisi, C Cressoni, N Vitulo, V Dusi, A Speghini, T Pandolfini

Open access · goldAbstract read
In one paragraph

Article in Nanoscale advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Regulation of Plant Genes with Exogenous RNAs.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Regulation of Anthocyanin Accumulation in TomatoPlants (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Impact of Exogenous dsRNA on miRNA Composition inPlants (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

B MolesiniDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.ORCID https://orcid.org/0000-0002-4324-4908
F PennisiDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.
C CressoniDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.ORCID https://orcid.org/0000-0002-4539-7027
N VituloDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.
V DusiDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.
A SpeghiniDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.ORCID https://orcid.org/0000-0002-6840-0006
T PandolfiniDepartment of Biotechnology, University of Verona Strada Le Grazie, 15 37134 Verona Italy barbara.molesini@univr.it.ORCID https://orcid.org/0000-0002-1658-2231
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi) is a post-translational regulatory mechanism that controls gene expression in plants. This process can be artificially induced by double-stranded RNA (dsRNA) molecules with sequence homology to target mRNAs. Exogenously applied dsRNA on leaves has been shown to silence virulence genes of fungi and viruses, conferring protection to plants. Coupling dsRNA to nanoparticles has been demonstrated to prolong the silencing effect. The ability of exogenous dsRNA to silence endogenous genes in plants is currently under debate, mainly due to the difficulty in delivering dsRNA into plant tissues and organs. Our study aims to develop a method based on the exogenous application of dsRNA on tomato flowers for silencing endogenous genes controlling ovary growth. Two methods of dsRNA delivery into tomato flower buds (

Identifiers

PMID36341284
PMCPMC9595187
OpenAlexW4295559691

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.