Evidence map›Paper›PMID 36341281›Full record

ArticleBiomarker insights2022

MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation.

Jennifer Crow, Glenson Samuel, Emily Farrow, Margaret Gibson, Jefferey Johnston, Erin Guest, Neil Miller, Dong Pei, Devin Koestler, Harsh Pathak and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biomarker insights, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Jennifer CrowDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Glenson SamuelChildren's Mercy Kansas City, Kansas City, MO, USA.
Emily FarrowThe Center for Pediatric Genomic Medicine at Children's Mercy, Kansas City, MO, USA.
Margaret GibsonThe Center for Pediatric Genomic Medicine at Children's Mercy, Kansas City, MO, USA.
Jefferey JohnstonThe Center for Pediatric Genomic Medicine at Children's Mercy, Kansas City, MO, USA.
Erin GuestChildren's Mercy Kansas City, Kansas City, MO, USA.
Neil MillerThe Center for Pediatric Genomic Medicine at Children's Mercy, Kansas City, MO, USA.
Dong PeiThe Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.
Devin KoestlerThe University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS, USA.
Harsh PathakDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Xiaobo LiangDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Cooper MangelsDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Andrew K GodwinDepartment of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Children's Mercy Hospital · USUniversity of Kansas Medical Center · USThe University of Kansas Cancer Center · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NICOLE L NOLLEN · 2012 to 2026
$40.1M
Using Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ANDREW K. GODWIN · 2019 to 2026
$21.5M
Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancerR33CA214333 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI GODWIN, ANDREW K., SAMUEL, GLENSON · 2017 to 2019
$1.2M
NCI NIH HHS P30 CA168524NCI NIH HHS R33 CA214333NIGMS NIH HHS P20 GM130423
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkersEwing SarcomaEwing Sarcoma Family of TumorsEWS-FLI1 fusionsexo-miRNAsexosomesliquid biopsymicroRNASmall extracellular vesicles

Identifiers

PMID36341281
PMCPMC9629554
OpenAlexW4308553368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.