Evidence map›Paper›PMID 36341270›Full record

ArticleFrontiers in medicine2022

Case report: Detection of anti-bullous pemphigoid antigen 180 antibodies in a patient with Behçet's disease.

Dario Didona, Antonio Manuel Sequeira Santos, Tomas Cunha, Julia Hinterseher, Jacqueline Kussini, Michael Hertl

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dario DidonaDepartment of Dermatology and Allergology, Philipps-University Marburg, Marburg, Germany.
Antonio Manuel Sequeira SantosDepartment of Dermatology and Allergology, Philipps-University Marburg, Marburg, Germany.
Tomas CunhaDepartment of Dermatology and Allergology, Philipps-University Marburg, Marburg, Germany.
Julia HinterseherDepartment of Dermatology and Allergology, Philipps-University Marburg, Marburg, Germany.
Jacqueline KussiniDepartment of Dermatology and Allergology, Philipps-University Marburg, Marburg, Germany.
Michael HertlDepartment of Dermatology and Allergology, Philipps-University Marburg, Marburg, Germany.
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's disease (BD) is a systemic inflammatory disease of unknown etiology. BD is characterized by relapsing oral and genital ulcers, several different cutaneous features, relapsing bilateral uveitis, and involvement of internal organs, showing vascular, gastrointestinal, and neurological manifestations. Serologically, BD is not characterized by disease-specific autoantibodies. In fact, only laboratory markers of inflammation, such as C-reactive protein, may be increased in association with increased disease activity. Bullous pemphigoid (BP) is an autoimmune disease characterized mainly by tense blisters and urticaria-like plaques on the skin. In addition, BP can involve oral mucosa in up to 20% of patients. Patients with BP show serum IgG autoantibodies against BP antigen 180 (BP180) and/or BP antigen 230 (BP230). Tissue-bound autoantibodies can be visualized as linear IgG staining along the basement membrane by direct immunofluorescence microscopy. In this report, we first described a young patient with BD who showed IgG autoantibodies against BP180 without developing blisters or urticaria-like plaques.

Indexed as

autoantibodiesBehçet’s diseasebullous pemphigoiddiagnosisepitope spreading

Identifiers

PMID36341270
PMCPMC9632984
OpenAlexW4306946080

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.