Evidence map›Paper›PMID 36341214›Full record

ArticleJACC. Asia2021

Clinical Impact of Lesion Complexity on 2-Year Outcomes After Zotarolimus-Eluting Stents Implantation.

Jung-Ho Park, Cheol Hyun Lee, Yun-Kyeong Cho, Hyuck-Jun Yoon, Chang-Wook Nam, Jong Seon Park, Kee-Sik Kim, Hun Sik Park, Bong-Ryeol Lee, Eun-Seok Shin and 3 more

Abstract read
In one paragraph

Article in JACC. Asia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jung-Ho ParkDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea.
Cheol Hyun LeeDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea.
Yun-Kyeong ChoDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea.
Hyuck-Jun YoonDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea.
Chang-Wook NamDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea.
Jong Seon ParkDivision of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, South Korea.
Kee-Sik KimDivision of Cardiology, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, South Korea.
Hun Sik ParkDivision of Cardiology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, South Korea.
Bong-Ryeol LeeDivision of Cardiology, Department of Internal Medicine, Daegu Fatima Hospital, Daegu, South Korea.
Eun-Seok ShinDivision of Cardiology, Department of Internal Medicine, Ulsan University Hospital, Seoul, South Korea.
Jang-Ho BaeDivision of Cardiology, Department of Internal Medicine, Konyang University Hospital, Nonsan, South Korea.
Young Dae KimDivision of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, South Korea.
Seung-Ho HurDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The clinical efficacy and safety of second-generation drug-eluting stents in complex percutaneous coronary interventions (PCIs) are not well established. Objectives: The clinical influence of the lesion complexity after PCI with zotarolimus-eluting stents (ZES) was evaluated. Methods: From a prospective multicenter observational study, a total of 926 patients that underwent successful PCIs with ZES were included. Complex PCIs were defined as patients with ≥3 lesions treated, 3 vessels treated, severe calcified lesions, bifurcated lesions with 2 stents implanted, left main disease, chronic total occlusion lesions, and/or diffuse long (total stent length ≥60 mm) lesions and were compared to the noncomplex group. The primary outcome was incidence of target lesion failures at 2 years, defined as a composite of cardiac death, target lesion-myocardial infarctions, and target lesion revascularization. Results: The patients were divided into complex PCI (n = 249) and noncomplex (n = 677) groups. In the complex PCI group, the 2-year risk of a target lesion failure was not significantly higher than in the noncomplex PCI group (4.8% vs 3.7%; adjusted hazard ratio: 1.373; 95% confidence interval: 0.689-2.738; Conclusions: Up to 2 years after a ZES implantation, the clinical outcomes did not differ according to lesion complexity.

Indexed as

CKD, chronic kidney diseasecomplex percutaneous coronary artery interventioncoronary artery diseaseDES, drug-eluting stent(s)drug-eluting stentsIVUS, intravascular ultrasoundMACE, major adverse cardiac eventsMI, myocardial infarctionOCT, optical coherence tomographyPCI, percutaneous coronary interventionTLF, target lesion failureTLR, target lesion revascularizationZES, zotarolimus-eluting stent(s)

Identifiers

PMID36341214
PMCPMC9627827

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.