Evidence map›Paper›PMID 36341209›Full record

ArticleJACC. Asia2021

Prognosis and Outcomes of Clinically Diagnosed Cardiac Sarcoidosis Without Positive Endomyocardial Biopsy Findings.

Kengo Kusano, Kohei Ishibashi, Takashi Noda, Kenzaburo Nakajima, Kosuke Nakasuka, Satoshi Terasaki, Yusuke Hattori, Tomomi Nagayama, Kazuki Mori, Yoichi Takaya and 10 more

Abstract read
In one paragraph

Article in JACC. Asia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Characteristics and incidence of cardiac events across spectrum of age in cardiac sarcoidosis.International journal of cardiology. Heart & vasculature · 2024
    Article
  15. Exploring the latest advances inAmerican journal of nuclear medicine and molecular imaging · 2024
    Review
  16. Sarcoid heart disease and imaging.Heart rhythm O2 · 2024
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Kengo KusanoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kohei IshibashiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Takashi NodaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kenzaburo NakajimaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kosuke NakasukaDepartment of Cardio-Renal Medicine and Hypertension, Nagoya City University, Nagoya, Japan.
Satoshi TerasakiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yusuke HattoriDepartment of Cardiovascular Medicine, Shizuoka City Shizuoka Hospital, Shizuoka, Japan.
Tomomi NagayamaDepartment of Cardiovascular Medicine, Fukuoka City Hospital, Fukuoka, Japan.
Kazuki MoriDepartment of Cardiovascular Medicine, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.
Yoichi TakayaDepartment of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Okayama, Japan.
Koji MiyamotoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Satoshi NagaseDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Takeshi AibaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Satoshi YasudaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Masafumi KitakazeDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Shiro KamakuraDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yoshikazu YazakiDepartment of Cardiovascular Medicine, Saku Central Hospital Advanced Care Center, Nagano, Japan.
Shin-Ichiro MorimotoDepartment of Cardiovascular Medicine, Fujita Health University, Aichi, Japan.
Mitsuaki IsobeDepartment of Cardiovascular Medicine, Sakakibara Heart Institute, Tokyo, Japan.
Fumio TerasakiMedical Education Center/Department of Cardiology, Osaka Medical College, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diagnosis of cardiac sarcoidosis (CS) is sometimes difficult due to a low positive rate of epithelioid granulomas by endomyocardial biopsy (EMB). Accordingly, Japanese guidelines can allow the CS diagnosis using clinical data alone without EMB results (clinical CS) since 2006. However, little is known about prognosis and outcome of clinical CS. Objectives: Purpose of this study was to analyze the prognosis, outcomes, and response to corticosteroid of clinical CS using large-scale cohort survey. Methods: Overall, 422 CS patients (mean age 60 ± 13 years, 68% female, median follow-up period of 5 years), including 345 clinical CS and 77 EMB-positive patients, histologically diagnosed CS (histological CS) by Japanese guidelines, were enrolled and examined. Results: Clinical profile (age, sex, initial cardiac arrhythmias, and abnormal uptake of gallium-67 scintigraphy or Conclusions: In clinical CS according to the Japanese guideline, prophylactic implantable-cardioverter-defibrillator and immunosuppressive therapy are important in patients with low LVEF or ventricular tachycardia history, similar to histological CS.

Indexed as

18F-FDG, 18F-fluorodeoxyglucose67Ga, gallium-67AVB, atrioventricular blockBAL, bronchoalveolar lavagecardiac sarcoidosisclinical diagnosisCMR, cardiac magnetic resonanceCRT, cardiac resynchronization therapyCS, cardiac sarcoidosisEMB, endomyocardial biopsyhistological diagnosisHRS, Heart Rhythm SocietyICD, implantable cardioverter-defibrillatorJCS, Japanese Circulation SocietyJSSOG, Japanese Society of Sarcoidosis and Other Granulomatous diseasesLVEF, left ventricular ejection fractionLV, left ventricularPET, positron emission tomographyprognosisRFCA, radiofrequency catheter ablationRV, right ventricle/ventricularVT, ventricular tachycardia

Identifiers

PMID36341209
PMCPMC9627866

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.