ArticleFrontiers in neurology2022
The impact of COVID-19 pandemic on treatment delay and short-term neurological functional prognosis for acute ischemic stroke during the lockdown period.
Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Epidemiological Shifts and Trends From 2009 to 2023 in Hospital Admissions for Ruptured Aortic Aneurysms and Aortic Dissections in Austria: Retrospective, Population-Wide Study.JMIR public health and surveillance · 2026Article
- Association Between Sociodemographic Disparities and Door to Computerized Tomography Time in Patients with Acute Ischemic Stroke Across COVID-19 Periods in the Emergency Department: A Multi-Center Cohort Study.Medical sciences (Basel, Switzerland) · 2025Article
- The impacts of mask-wearing regulations on stroke morbidity and mortality: a population-based retrospective cohort study in China.BMC public health · 2024Article
- COVID-19 Infection Is Associated With Poor Outcomes in Patients With Intracerebral Hemorrhage.Journal of the American Heart Association · 2024Observational
- Impact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience.Frontiers in neurology · 2024Article
- Increased time to surgery and worse perioperative outcome in benign brain tumor patients with COVID-19.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2023Article
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Preventive strategies implemented during the COVID-19 pandemic may negatively influence the management of patients with acute ischemic stroke (AIS). Nowadays, studies have demonstrated that the pandemic has led to a delay in treatment among patients with AIS. Whether this delay contributes to meaningful short-term outcome differences warranted further exploration. Objective: The objective of this study was to evaluate the impacts of the COVID-19 pandemic on treatment delay and short-term outcomes of patients with AIS treated with IVT and MT. Methods: Patients admitted before (from 11/1/2019 to 1/31/2020) and during the COVID-19 pandemic (from 2/1/2020 to 3/31/2020) were screened for collecting sociodemographic data, medical history information, and symptom onset status, and comparing the effect of treatment delay. The patients treated with IVT or MT were compared for delay time and neurological outcomes. Multivariable logistic regression was used to estimate the effect of treatment delay on short-term neurological prognosis. Results: In this study, 358 patients receiving IVT were included. DTN time increased from 50 min (IQR 40-75) before to 65 min (IQR 48-84), Conclusion: The COVID-19 pandemic has had remarkable impacts on the management of AIS. The pandemic might exacerbate certain time delays and play a significant role in early adverse outcomes in patients with AIS.
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