Evidence map›Paper›PMID 36341055›Full record

ArticleVeterinary world2022

Exposure to high thermal conditions for a long time induces apoptosis and decreases total RNA concentration in peripheral blood mononuclear cells among Indian Zebu-Jersey crossbreds.

Gbolabo Olaitan Onasanya, George M Msalya, Aranganoor K Thiruvenkadan, Nagarajan Murali, Ramasamy Saravanan, Angamuthu Raja, Moses Okpeku, Mani Jeyakumar, Christian O Ikeobi

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Gbolabo Olaitan OnasanyaDepartment of Animal Science, Federal University Dutse, Dutse, Nigeria.
George M MsalyaDepartment of Animal, Aquaculture and Range Sciences, Sokoine University of Agriculture, Morogoro, Tanzania.
Aranganoor K ThiruvenkadanDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.
Nagarajan MuraliDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.
Ramasamy SaravananDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.
Angamuthu RajaDepartment of Veterinary Microbiology, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.
Moses OkpekuDiscipline of Genetics, School of Life Sciences, College of Agriculture, Engineering and Sciences, University of KwaZulu-Natal (Westville Campus), Durban, South Africa.
Mani JeyakumarDepartment of Animal Genetics and Breeding, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.
Christian O IkeobiDepartment of Animal Breeding and Genetics, Federal University of Agriculture, Abeokuta, Nigeria.
Tamil Nadu Veterinary and Animal Sciences University · INFederal University of Agriculture · NGSokoine University of Agriculture · TZUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Global warming has grave consequences on livestock production systems and profound negative effects on animal production. This study aimed to carry out an Materials and Methods: Ten milliliters of blood were collected from 70 Indian Zebu-Jersey crossbreds under aseptic conditions and were sampled for isolating PBMCs. Peripheral blood mononuclear cells were divided into seven groups, each comprising 10 PBMC samples isolated from 10 different animals. Aliquots of 500 μL of PBMCs were stressed by exposure to different TACs (37, 40, and 45°C) for DTEs of 3 or 6 h. Subsequently, the cells were harvested. The control unstressed samples (500 μL aliquots of PBMCs) were exposed to no TAC (0°C) and zero DTE (0 h). Total RNA from all the treatment groups of PBMCs were isolated and quantitated. Results: We found a very strong association between TACs and RNA levels. In addition, PBMCs viability was negatively affected by heat shock. This led to an exponential reduction in PBMC count as TACs toughened. Only 3.59 × 10 Conclusion:

Indexed as

bovinecell survivalclimate changeperipheral blood mononuclear cellsRNA synthesisthermal stress

Identifiers

PMID36341055
PMCPMC9631357
OpenAlexW4295807270

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.