Evidence map›Paper›PMID 36340808›Full record

ArticleGastroenterology report2022

Endoscopic ultrasound fine-needle biopsy vs fine-needle aspiration for lymph nodes tissue acquisition: a systematic review and meta-analysis.

Antonio Facciorusso, Stefano Francesco Crinò, Paraskevas Gkolfakis, Daryl Ramai, Andrea Lisotti, Ioannis S Papanikolaou, Benedetto Mangiavillano, Ilaria Tarantino, Andrea Anderloni, Carlo Fabbri and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Gastroenterology report, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Approach to management of bleeding during EUS-guided liver biopsy: salvage therapy using absorbable gelatin sponge.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 4 countries.

Antonio FacciorussoGastroenterology Unit, Department of Surgical and Medical Sciences, University of Foggia, Foggia, Italy.
Stefano Francesco CrinòDepartment of Medicine, Gastroenterology and Digestive Endoscopy Unit, The Pancreas Institute, University Hospital of Verona, Verona, Italy.
Paraskevas GkolfakisDepartment of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB Erasme Hospital, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Daryl RamaiGastroenterology and Hepatology, University of Utah Health, Salt Lake City, UT, USA.
Andrea LisottiGastroenterology Unit, Hospital of Imola, University of Bologna, Imola, Italy.ORCID https://orcid.org/0000-0002-7724-7402
Ioannis S PapanikolaouHepatogastroenterology Unit, Second Department of Internal Medicine-Propaedeutic, Medical School, National and Kapodistrian University of Athens, 'Attikon' University General Hospital, Athens, Greece.
Benedetto MangiavillanoGastrointestinal Endoscopy Unit, Humanitas Mater Domini, Castellanza, Varese, Italy.
Ilaria TarantinoEndoscopy Service, Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT, Palermo, Italy.
Andrea AnderloniDigestive Endoscopy Unit, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milano, Italy.
Carlo FabbriGastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, AUSL Romagna, Forlì-Cesena, Italy.
Konstantinos TriantafyllouHepatogastroenterology Unit, Second Department of Internal Medicine-Propaedeutic, Medical School, National and Kapodistrian University of Athens, 'Attikon' University General Hospital, Athens, Greece.
Pietro FusaroliGastroenterology Unit, Hospital of Imola, University of Bologna, Imola, Italy.
National and Kapodistrian University of Athens · GRUniversity of Bologna · ITAzienda-Unita' Sanitaria Locale Di Cesena · ITHumanitas Mater Domini · ITHumanitas University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversité Libre de Bruxelles · BEUniversity of Foggia · ITUniversity of Utah · USUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endoscopic ultrasound (EUS)-guided tissue acquisition represents the choice of methods for suspected lymph nodes (LNs) located next to the gastrointestinal tract. This study aimed to compare the pooled diagnostic performance of EUS-guided fine-needle biopsy (EUS-FNB) and fine-needle aspiration (EUS-FNA) for LNs sampling. Methods: We searched PubMed/MedLine and Embase databases through August 2021. Primary outcome was diagnostic accuracy; secondary outcomes were sensitivity, specificity, sample adequacy, optimal histological core procurement, number of passes, and adverse events. We performed a pairwise meta-analysis using a random-effects model. The results are presented as odds ratio (OR) or mean difference along with 95% confidence interval (CI). Results: We identified nine studies (1,276 patients) in this meta-analysis. Among these patients, 66.4% were male; the median age was 67 years. Diagnostic accuracy was not significantly different between the two approaches (OR, 1.31; 95% CI, 0.81-2.10; Conclusions: EUS-FNA and EUS-FNB perform similarly in LN sampling; however, FNB performed with end-cutting needles outperformed FNA in terms of diagnostic accuracy.

Indexed as

cancerEUSFNAFNBlymphomametastases

Identifiers

PMID36340808
PMCPMC9632631
OpenAlexW4308551879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.