Evidence map›Paper›PMID 36340795›Full record

ArticleFrontiers in neuroscience2022

Network pharmacology analysis reveals neuroprotective effects of the Qin-Zhi-Zhu-Dan Formula in Alzheimer's disease.

Wenxiu Xu, Beida Ren, Zehan Zhang, Congai Chen, Tian Xu, Shuling Liu, Chongyang Ma, Xueqian Wang, Qingguo Wang, Fafeng Cheng

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wenxiu XuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Beida RenDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Zehan ZhangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Congai ChenDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Tian XuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Shuling LiuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Chongyang MaSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Xueqian WangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Qingguo WangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Fafeng ChengSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is yet no effective drug for Alzheimer's disease (AD) which is one of the world's most common neurodegenerative diseases. The Qin-Zhi-Zhu-Dan Formula (QZZD) is derived from a widely used Chinese patent drug-Qing-Kai-Ling Injection. It consists of

Indexed as

Alzheimer’s diseaseinflammatory responsenetwork pharmacologyQin-Zhi-Zhu-Dan FormulaTNF signaling pathway

Identifiers

PMID36340795
PMCPMC9632440
OpenAlexW4306880412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.