ArticleFrontiers in pediatrics2022
The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention.
Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of integrated programs for substance-involved mothers on infant and child development outcomes: A systematic review and meta-analysis.Infant mental health journal · 2025Pooled it
- Neonatal Toxicology Testing: Ethical Considerations for Pediatricians.Hospital pediatrics · 2026Article
- Segmental Trunk Control in Sitting Between Full-Term and Preterm Infants Raised in the Orphanage Setting.International journal of environmental research and public health · 2025Article
- Pathologies in a preterm infant exposed to methamphetamine in utero: Case report and literature review.Radiology case reports · 2025Article
- Multi-method approach effectively identifies and engages children impacted by parental substance misuse into school-based prevention services.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/objectives: Maternal illicit drug use is associated with negative physical and developmental outcomes for their born children. We aim to find out the incidence of different developmental problems in a cohort of Chinese children born to drug-abusing mothers, compare the physical health and developmental outcomes of the subjects recruited in the Integrated Program to the Comprehensive Child Development Service (CCDS), and to study the potential factors on their associations. Methods: A retrospective longitudinal cohort study with frequent clinical assessments of the children's physical and developmental outcomes in a HKSAR's regional hospital from birth until 5 years old. 123 Children in Integrated Program were compared with 214 children in CCDS between 1 January 2008 and 28 February 2019. Cox regression analysis was performed to determine the possible factors associated with the developmental outcomes. Results: Developmental delay was detected in 129 children (38.9%). CCDS group has significantly higher incidence of cognitive delay ( Conclusion: CCDS achieves early engagement of drug-abusing expectant mothers during pregnancy, and an early integrated program with multidisciplinary collaboration was an independent factor in improving the developmental outcomes of these vulnerable children.
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Registered trials
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