ArticleHeart rhythm O22022
Healthcare utilization and costs associated with a diagnosis of incident atrial fibrillation.
Article in Heart rhythm O2, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Minimally invasive thoracoscopic surgical ablation and hybrid ablation in AF patients: results from a single-arm systematic review and meta-analysis.Journal of cardiothoracic surgery · 2026Pooled it
- 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2024Guideline
- Guideline
- Augmenting Engagement in Decentralized Clinical Trials for Atrial Fibrillation: Development and Implementation of a Programmatic Architecture.JMIR cardio · 2025Trial
- Cost-effectiveness of digoxin versus beta blockers in permanent atrial fibrillation: the Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF) randomised trial.Heart (British Cardiac Society) · 2025Trial
- How much should the resting heart rate be controlled in patients with atrial fibrillation and coronary heart disease?BMC cardiovascular disorders · 2024Trial
- Clinical and Epidemiological Profile of Atrial Fibrillation in a High-Altitude Tertiary-Care Setting.Medicina (Kaunas, Lithuania) · 2026Article
- NovelBiomedicines · 2026Article
- Kill Four Birds With One Stone: Ablation of Atrial Fibrillation, Atrial Flutter, and Supraventricular Tachycardia Plus Left Atrial Appendage.Journal of medical cases · 2026Article
- Impact of atrioventricular node ablation and permanent pacing on clinical outcomes, quality of life, and health care utilization in patients with atrial fibrillation.Heart rhythm O2 · 2026Article
- Rare TruncatingGenes · 2026Article
- Trends in atrial fibrillation/atrial flutter and cirrhosis-related mortality in the United States from 1999 to 2020: a CDC WONDER analysis.Annals of medicine and surgery (2012) · 2026Review
- Comprehensive Analysis of Atrial Fibrillation/Atrial Flutter Burden in the United States and the European Union: A Comparison and Assessment of Trends and Risk Factors.Journal of cardiovascular development and disease · 2026Article
- Rural-urban disparities in atrial fibrillation-related diagnostic testing and medical procedures in Canada†.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- The Role of Ethanol Ablation of the Vein of Marshall in the Era of Pulsed Field Ablation.Journal of clinical medicine · 2026Review
- Medical Costs and Productivity Losses of Atrial Fibrillation Among US Privately Insured Employees.JAMA network open · 2026Article
- Patient and Procedural Factors Associated With Same-Day Discharge Following Pulsed Field Ablation for Atrial Fibrillation: Insights From the DISRUPT-AF Registry.Journal of cardiovascular electrophysiology · 2026Observational
- Low serum zinc levels and risk of incident atrial fibrillation/flutter: a multi-institutional study.Frontiers in nutrition · 2026Article
- Discovery ofDiagnostics (Basel, Switzerland) · 2025Article
- Monitoring Atrial Fibrillation Using Wearable Digital Technologies: The Emerging Role of Smartwatches.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Atrial fibrillation (AF) is the most common heart rhythm disorder among adults and leads to substantial morbidity and mortality. Objectives: The purpose of the study was to provide current estimates on the incremental healthcare utilization and cost burden associated with incident AF diagnosis in the United States. Methods: Adults with an incident diagnosis of AF (2017-2020) were identified using the Optum Clinformatics database. Propensity matching was employed to match patients with incident AF to a comparator group of non-AF patients on several demographic and clinical characteristics. Outcomes including 12-month all-cause and cardiovascular (CV)-related healthcare utilization, as well as the medical cost associated with health services use, were assessed. Logistic and general linear models were used to examine study outcomes. Sub-analyses were performed to determine the incremental AF burden by specific sex and racial/ethnic categories. Results: A total of 79,621 patients were identified in each cohort (AF and non-AF). As compared to the non-AF cohort, patients with AF had significantly higher all-cause inpatient visits (relative risk [RR] 1.77; 95% confidence interval [CI] 1.76-1.78), CV-related inpatient visits (RR 2.51; 95% CI 2:49-2:53), and CV-related emergency room visits (RR: 2.41; 95% CI 2:35-2:47). The mean total healthcare cost for patients with AF was $27,896 more (per patient per year) than the non-AF cohort ($63,031 vs $35,135, Conclusion: Medical services utilization and cost were significantly higher among AF patients than non-AF patients. Early treatment is likely to be critical to addressing the considerable disease burden imposed by AF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.