Evidence map›Paper›PMID 36340450›Full record

ArticleCancer diagnosis & prognosis

Prognostic Factors for Survival in Patients With High-grade Chondrosarcoma.

Hideyuki Kinoshita, Hiroto Kamoda, Yoko Hagiwara, Seiko Kinoshita, Seiji Ohtori, Tsukasa Yonemoto

Open access · greenAbstract read
In one paragraph

Article in Cancer diagnosis & prognosis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Association of Cartilage Cap Thickness With Tumor Grade and Outcomes in Secondary Chondrosarcoma.The Journal of the American Academy of Orthopaedic Surgeons · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hideyuki KinoshitaDepartment of Orthopedic Surgery, Chiba Cancer Center, Chiba, Japan.
Hiroto KamodaDepartment of Orthopedic Surgery, Chiba Cancer Center, Chiba, Japan.
Yoko HagiwaraDepartment of Orthopedic Surgery, Chiba Cancer Center, Chiba, Japan.
Seiko KinoshitaLaboratory of Oncogenomics, Chiba Cancer Center Research Institute, Chiba, Japan.
Seiji OhtoriDepartment of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Tsukasa YonemotoDepartment of Orthopedic Surgery, Chiba Cancer Center, Chiba, Japan.
Chiba Cancer Center · JPChiba University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimChondrosarcoma (CS) is a rare primary malignant bone tumor, which is the second most common tumor after osteosarcoma. Since chemotherapy and radiotherapy have poor efficacy for CS, amputation or surgical wide resection is the main strategy for localized high-grade CS, making CS therapy difficult. As studies on high-grade CS are limited owing to its rare nature, there are many unknown prognostic factors for survival. PATIENTS AND

methodsThis retrospective cohort study included 44 patients with high-grade CS who underwent surgery at a single institution. Overall survival (OS), distant failure-free survival (DFFS), and local failure-free survival (LFFS) were evaluated using the Kaplan-Meier method. Furthermore, we evaluated prognostic factors for survival in patients with high-grade CS using univariate and multivariate analyses.

resultsThe 5-year OS, LFFS, and DFFS rates of high-grade CS were 75.9%, 90.8%, and 66.5%, respectively. Univariate analysis revealed that tumor size, tumor grade, and surgical margin were significant prognostic factors for OS and DFFS, and distant metastasis was significantly associated with OS. Furthermore, the multivariate analysis indicated that the presence of local recurrence and distant metastasis was significantly associated with OS.

conclusionLocal recurrence and distant metastasis were significant prognostic factors for high-grade CS.

Indexed as

Chondrosarcomadistant metastasislocal recurrenceoverall survivalprognostic factor

Identifiers

PMID36340450
PMCPMC9628161
OpenAlexW4308550322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.