Evidence map›Paper›PMID 36340306›Full record

ReviewJournal of clinical and experimental hepatology

Management of Alcohol Withdrawal Syndrome in Patients with Alcoholic Liver Disease.

Prabhat Kumar Chand, Udit Panda, Jayant Mahadevan, Pratima Murthy

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Alcohol-Associated Liver Disease - From Pathogenesis to Treatment.Journal of clinical and experimental hepatology
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Prabhat Kumar ChandCentre for Addiction Medicine, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Udit PandaKalinga Institute of Medical Sciences, Bhubaneshwar, India.
Jayant MahadevanCentre for Addiction Medicine, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Pratima MurthyNational Institute of Mental Health and Neurosciences, Bangalore, India.
National Institute of Mental Health and Neurosciences · INAll India Institute of Medical Sciences Bhubaneswar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol withdrawal syndrome (AWS) is a common condition that is seen in treatment-seeking patients with Alcohol use disorder (AUD) and alcoholic liver disease (ALD). AWS, which typically starts within 4-6 h of the last alcohol use, can range from mild symptoms such as insomnia, tremors, and autonomic hyperactivity to more severe symptoms such as seizures and delirium tremens. Clinical Institute Withdrawal Assessment Scale-Alcohol Revised (CIWA-Ar) is the most commonly used scale to assess AWS in clinical practice. The presence of moderate withdrawal as indicated by a score of more than 8 is an indication for pharmacotherapy. Lorazepam and oxazepam are preferred agents for the management of AWS in the setting of ALD. In severe ALD, benzodiazepines should be used cautiously with monitoring due to the risk of excessive sedation or precipitating hepatic encephalopathy.

Indexed as

alcoholalcoholic liver diseaseALD, alcoholic liver diseaseAMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acidassessmentAUD, alcohol use disorderAUDIT, Alcohol Use Disorder Identification TestAUDIT – C, Alcohol Use Disorder Identification Test – ConsumptionAWS, alcohol withdrawal syndromeCIWA – Ar, Clinical Institute Withdrawal Assessment for Alcohol RevisedCNS, central nervous systemEtG, ethyl glucuronideEtS, ethyl sulphateGABA, gamma-aminobutyric acidGGT, gamma glutamyl transferaseHE, hepatic encephalopathyMCV, mean corpuscular volumeNMDA, N-methyl-d-aspartatetreatmentwithdrawal

Identifiers

PMID36340306
PMCPMC9630022
OpenAlexW4226047420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.