Evidence map›Paper›PMID 36340303›Full record

ReviewJournal of clinical and experimental hepatology

Management of Alcohol Use Disorder in Patients With Alcoholic Liver Disease.

Pratima Murthy, Darshan Shadakshari, Jayant Mahadevan, Prabhat Kumar Chand

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. The Role of Patient-Reported Outcomes in Cirrhosis.The American journal of gastroenterology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Alcohol-Associated Liver Disease - From Pathogenesis to Treatment.Journal of clinical and experimental hepatology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pratima MurthyNational Institute of Mental Health and Neurosciences, Bangalore, India.
Darshan ShadakshariCentre for Addiction Medicine, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Jayant MahadevanCentre for Addiction Medicine, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Prabhat Kumar ChandCentre for Addiction Medicine, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
National Institute of Mental Health and Neurosciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol use disorder (AUD) is a common condition that develops on the background of heavy alcohol use and is characterised by the loss of control over alcohol use and a compulsion to use alcohol, often despite negative consequences. AUD is a leading cause for the resumption of alcohol use in patients with alcoholic liver disease (ALD) after treatment. Hence it is essential to screen all patients with ALD for the presence of AUD. Screening tools such as alcohol use disorders identification test (AUDIT) and AUDIT-C are used, following which the diagnosis and severity of AUD are determined using DSM-5 criteria. The management of AUD in patients with ALD is best carried out using an integrated approach involving psychiatrists and gastroenterologists/hepatologists. The treatment most often involves a combination of pharmacotherapy and psychosocial interventions which try to achieve and maintain abstinence. Although, there is limited evidence, Baclofen is the first line pharmacological agent for long-term management of AUD in patients with ALD. Intensive psychological interventions such as motivation enhancement therapy and cognitive behavioural therapy are also seen to be beneficial. Treatment retention and follow-up are vital and can positively influence outcomes.

Indexed as

AA, Alcoholics Anonymousalcoholic liver diseasealcohol use disorderALD, Alcoholic Liver DiseaseAMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acidAUD, Alcohol Use DisorderAUDIT, Alcohol Use Disorder Identification TestAUDIT – C, Alcohol Use Disorder Identification Test – ConsumptionCBT, Cognitive Behavioural TherapyCDT, Carbohydrate Deficient TransferrinCIWA – Ar, Clinical Institute Withdrawal Assessment for Alcohol RevisedDALY, Disability Adjusted Life YearsdiagnosisEtG, Ethyl glucuronideEtS, Ethyl SulphateFAEE, Fatty acid ethyl esterFDA, Food and Drug AdministrationGABA, Gamma-Aminobutyric acidGGT, Gamma glutamyl transferaseHCV, Hepatitis C VirusHE, Hepatic EncephalopathyLT, Liver TransplantationMCV, Mean corpuscular volumeMET, Motivation Enhancement TherapyMI, Motivational InterviewingNMDA, N-Methyl-d-aspartatePEth, PhosphatidylethanolpharmacotherapypsychotherapyRCT, Randomised control trialSMS, Short Message Service

Identifiers

PMID36340303
PMCPMC9630026
OpenAlexW4224237898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.