Evidence map›Paper›PMID 36340256›Full record

ArticleJACC. Asia2022

Prognostic Impact of Echocardiographic Congestion Grade in HFpEF With and Without Atrial Fibrillation.

Haruhiko Abe, Shumpei Kosugi, Tatsuhisa Ozaki, Tsuyoshi Mishima, Motoo Date, Yasunori Ueda, Masaaki Uematsu, Shunsuke Tamaki, Masamichi Yano, Takaharu Hayashi and 10 more

Open access · goldAbstract read
In one paragraph

Article in JACC. Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

Haruhiko AbeCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Shumpei KosugiCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Tatsuhisa OzakiCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Tsuyoshi MishimaCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Motoo DateCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Yasunori UedaCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Masaaki UematsuCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Shunsuke TamakiDivision of Cardiology, Osaka General Medical Center, Osaka, Japan.
Masamichi YanoDivision of Cardiology, Osaka Rosai Hospital, Sakai, Japan.
Takaharu HayashiDivision of Cardiology, Osaka Police Hospital, Osaka, Japan.
Akito NakagawaDivision of Cardiology, Amagasaki Chuo Hospital, Amagasaki, Japan.
Yusuke NakagawaDivision of Cardiology, Kawanishi City Hospital, Kawanishi, Japan.
Takahisa YamadaDivision of Cardiology, Osaka General Medical Center, Osaka, Japan.
Yoshio YasumuraDivision of Cardiology, Amagasaki Chuo Hospital, Amagasaki, Japan.
Tomoharu DohiDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Shinichiro SunaDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Shungo HikosoDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Daisaku NakataniDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Yukihiro KoretsuneCardiovascular Division, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Yasushi SakataDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Osaka National Hospital · JPOsaka University · JPKishiwada City Hospital · JPOsaka City General Hospital · JPOsaka Police Hospital · JPOsaka Prefectural Medical Center · JPOsaka Rosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is common in heart failure with preserved ejection fraction (HFpEF). Objectives: This study aimed to investigate the prognostic value of echocardiographic markers of congestion that can be applied to both AF and patients without AF with HFpEF. Methods: We conducted a multicenter study of 505 patients with HFpEF admitted to hospitals for acute decompensated heart failure. The ratio of early diastolic transmitral flow velocity to mitral annulus velocity (E/e'), the tricuspid regurgitation peak velocity, and the collapsibility of the inferior vena cava were obtained at discharge. Congestion was determined by echocardiography if any one of E/e' ≥14 (E/e' ≥11 for AF), tricuspid regurgitation peak velocity ≥2.8 m/s, or inferior vena cava collapsibility <50% was positive. We classified patients into grade A, grade B, and grade C according to the number of positive congestion indices. The primary endpoint was the composite of cardiovascular death and heart failure hospitalization. Results: During the follow-up period (median: 373 days), 162 (32%) patients experienced the primary endpoint. Grade C patients had a higher risk for the primary endpoint than grade A (HR: 2.98; 95% CI: 1.97-4.52) and grade B patients (HR: 1.92; 95% CI: 1.29-2.86) (log-rank Conclusions: Echocardiographic congestion grade has prognostic value in patients with HFpEF with and without AF.

Indexed as

AF, atrial fibrillationASE, American Society of EchocardiographycongestionEACVI, European Association of Cardiovascular ImagingechocardiographyE/e′, ratio of early diastolic transmitral flow velocity to mitral annulus velocityheart failure with preserved ejection fractionHFpEF, heart failure with preserved ejection fractionIVCC, inferior vena cava collapsibilityIVC, inferior vena cavaNT-proBNP, N-terminal pro–B-type natriuretic peptideNYHA, New York Heart AssociationprognosisTRV, tricuspid regurgitation peak velocity

Identifiers

PMID36340256
PMCPMC9627800
OpenAlexW4205199753

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.