Evidence map›Paper›PMID 36339923›Full record

ArticleClinical pathology (Thousand Oaks, Ventura County, Calif.)

Immunopathology of Cutaneous Leishmaniasis in a Cohort of Sri Lankan Patients.

Harshima Disvini Wijesinghe, Gayani Kokila Wijesinghe, Deepika Fernando, Chandu de Silva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical pathology (Thousand Oaks, Ventura County, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Diagnostic Tools for Cutaneous Leishmaniasis Caused byDiagnostics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Harshima Disvini WijesingheDepartment of Pathology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Gayani Kokila WijesingheDepartment of Pathology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Deepika FernandoDepartment of Parasitology, Faculty of Medicine, University of Kelaniya, Sri Lanka.
Chandu de SilvaDepartment of Pathology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
University of Colombo · LKUniversity of Kelaniya · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction and objectives: Methodology: Fifty skin biopsies of cutaneous leishmaniasis confirmed by detection of organisms by histology, culture, slit-skin smear, and/or polymerase chain reaction were reviewed. The inflammatory infiltrate was characterized by immunohistochemical staining for CD4, CD8, CD20, and CD68. Associations and correlations between immunohistochemical staining pattern and the parasitic load, and patterns of inflammation were determined. Results: The majority of biopsies showed a CD8+/CD4- T lymphocyte predominant infiltrate (84%, n = 42). A CD68 predominant infiltrate was seen in 16%(n = 8). The mean percentage of CD8+, CD4+, CD20+, and CD68+ inflammatory cells in the biopsies were 56.1% (SD = 16.5%), 2.6% (SD = 4.5%), 12.3% (SD = 10.9%), and 25.7% (SD = 15.8%) respectively. There was no association between the predominant inflammatory cell and the degree of inflammation ( Discussion and Conclusion: Skin biopsies from cutaneous leishmaniasis due to

Indexed as

Cutaneous leishmaniasisimmune responseL. donovani infectionpathologySri Lanka

Identifiers

PMID36339923
PMCPMC9634189
OpenAlexW4308555238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.