Evidence map›Paper›PMID 36339856›Full record

ArticleFrontiers in psychiatry2022

Influence of clinical and neurocognitive factors in psychosocial functioning after a first episode non-affective psychosis: Differences between males and females.

Maria Serra-Navarro, Silvia Amoretti, Norma Verdolini, María Florencia Forte, Ana M Sánchez-Torres, Eduard Vieta, Derek Clougher, Antonio Lobo, Ana González-Pinto, Rocío Panadero and 9 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 3 countries.

Maria Serra-NavarroBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
Silvia AmorettiBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
Norma VerdoliniBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
María Florencia ForteBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
Ana M Sánchez-TorresDepartment of Psychiatry, Complejo Hospitalario de Navarra, Pamplona, Spain.
Eduard VietaBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
Derek ClougherBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
Antonio LoboBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
Ana González-PintoBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
Rocío PanaderoBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
Alexandra RoldánBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
André F CarvalhoInnovation in Mental and Physical Health and Clinical Treatment (IMPACT), School of Medicine, Barwon Health, The Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC, Australia.
Elena de la SernaBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
Alba TollBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
J A Ramos-QuirogaBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
Carla TorrentBipolar and Depressive Disorders Unit, Hospital Clinic of Barcelona, Institute of Neurosciences, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain.
Manuel J CuestaDepartment of Psychiatry, Complejo Hospitalario de Navarra, Pamplona, Spain.
Miguel BernardoBiomedical Research Networking Center for Mental Health Network (CIBERSAM), Barcelona, Spain.
PEPs Group
Centro de Investigación Biomédica en Red de Salud Mental · ESUniversitat Autònoma de Barcelona · ESComplejo Hospitalario de Navarra · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESBarwon Health · AUHospital General Universitario Gregorio Marañón · ESUniversity of Perugia · ITUniversity of the Basque Country · ES

Funding

NIMHD NIH HHS L60 MD003740
6 · The paper itself

Abstract

Background: Deficits in psychosocial functioning are present in the early stages of psychosis. Several factors, such as premorbid adjustment, neurocognitive performance, and cognitive reserve (CR), potentially influence functionality. Sex differences are observed in individuals with psychosis in multiple domains. Nonetheless, few studies have explored the predictive factors of poor functioning according to sex in first-episode psychosis (FEP). This study aimed to explore sex differences, examine changes, and identify predictors of functioning according to sex after onset. Materials and methods: The initial sample comprised 588 individuals. However, only adults with non-affective FEP ( Results: FEP improved their functionality at follow-up (67.4% of both males and females). In males, longer duration of untreated psychosis (β = 0.328, Conclusion: Our data indicate that predictors of functioning at 2-year follow-up in the FEP group differ according to sex. Therefore, treatment and preventative efforts may be adjusted taking sex into account. Males may benefit from functional remediation at early stages. Conversely, in females, early interventions centered on CR enhancement and cognitive rehabilitation may be recommended.

Indexed as

cognitionfirst episode non-affective psychosisnegative symptomspsychosocial functioningsex differences

Identifiers

PMID36339856
PMCPMC9632657
OpenAlexW4306980363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.