Evidence map›Paper›PMID 36339577›Full record

ArticleFrontiers in pharmacology2022

Untargeted metabolomics analysis of the hippocampus and cerebral cortex identified the neuroprotective mechanisms of Bushen Tiansui formula in an aβ

Hongli Li, Yejun Tan, Xin Cheng, Zheyu Zhang, Jianhua Huang, Shan Hui, Lemei Zhu, Yuqing Liu, Di Zhao, Zhao Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  7. Review
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    Article
  12. Review
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  15. Article
  16. New Approaches to the Treatment of Alzheimer's Disease.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  17. Neuroprotective Mechanisms ofMarine drugs · 2025
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Hongli LiDepartment of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Yejun TanSchool of mathematics, University of Minnesota twin Cities, St. Paul, MS, United States.
Xin ChengDepartment of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Zheyu ZhangDepartment of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Jianhua HuangHunan Academy of Chinese Medicine, Changsha, China.
Shan HuiDepartment of Geratology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Lemei ZhuAcademician Workstation, Changsha Medical University, Changsha, China.
Yuqing LiuDepartment of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Di ZhaoHunan Academy of Chinese Medicine, Changsha, China.
Zhao LiuHunan Academy of Chinese Medicine, Changsha, China.
Weijun PengDepartment of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Hunan Academy of Traditional Chinese Medicine · CNCentral South University · CNSecond Xiangya Hospital of Central South University · CNChangsha Medical University · CNHunan Normal University · CNNational Clinical Research Center for Digestive Diseases · CNUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseBushen Tiansui formulacerebral cortexhippocampusmetabolomics

Identifiers

PMID36339577
PMCPMC9630565
OpenAlexW4306929549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.