Evidence map›Paper›PMID 36339575›Full record

ReviewFrontiers in pharmacology2022

Bufadienolides originated from toad source and their anti-inflammatory activity.

Denglang Zou, Qiqi Wang, Tao Chen, Duocheng Sang, Tingqin Yang, Yuhan Wang, Mengze Gao, Fangfang He, Yulin Li, Liangliang He and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. 3CLJournal of computer-aided molecular design · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Resibufogenin: An Emerging Therapeutic Compound with Multifaceted Pharmacological Effects - A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Denglang ZouSchool of Life Science, Qinghai Normal University, Xining, China.
Qiqi WangCollege of Pharmacy, Jinan University, Guangzhou, China.
Tao ChenNorthwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China.
Duocheng SangSchool of Life Science, Qinghai Normal University, Xining, China.
Tingqin YangSchool of Life Science, Qinghai Normal University, Xining, China.
Yuhan WangSchool of Life Science, Qinghai Normal University, Xining, China.
Mengze GaoSchool of Life Science, Qinghai Normal University, Xining, China.
Fangfang HeSchool of Life Science, Qinghai Normal University, Xining, China.
Yulin LiNorthwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China.
Liangliang HeCollege of Pharmacy, Jinan University, Guangzhou, China.
Duojie LongzhuSchool of Life Science, Qinghai Normal University, Xining, China.
Qinghai Normal University · CNXinjiang Institute of Ecology and Geography · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bufadienolide, an essential member of the C-24 steroid family, is characterized by an α-pyrone positioned at C-17. As the predominantly active constituent in traditional Chinese medicine of Chansu, bufadienolide has been prescribed in the treatment of numerous ailments. It is a specifically potent inhibitor of Na

Indexed as

anti-inflammatory activityMS fragmentation principlesstructure diversitystructure modificationtoad sourced bufadienolide

Identifiers

PMID36339575
PMCPMC9627299
OpenAlexW4306843230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.