Evidence map›Paper›PMID 36339515›Full record

ArticleFrontiers in digital health2022

Personalized decision-making for acute cholecystitis: Understanding surgeon judgment.

Amanda C Filiberto, Philip A Efron, Amanda Frantz, Azra Bihorac, Gilbert R Upchurch, Tyler J Loftus

Open access · goldAbstract read
In one paragraph

Article in Frontiers in digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Amanda C FilibertoDepartment of Surgery, University of Florida Health, Gainesville, FL, United States.
Philip A EfronDepartment of Surgery, University of Florida Health, Gainesville, FL, United States.
Amanda FrantzDepartment of Anesthesiology, University of Florida Health, Gainesville, FL, United States.
Azra BihoracDepartment of Medicine, University of Florida Health, Gainesville, FL, United States.
Gilbert R UpchurchDepartment of Surgery, University of Florida Health, Gainesville, FL, United States.
Tyler J LoftusDepartment of Surgery, University of Florida Health, Gainesville, FL, United States.
University of Florida Health · US

Funding

PICS: A New Horizon for Surgical Critical CareP50GM111152 · NIGMS · UNIVERSITY OF FLORIDA · PI MOLDAWER, LYLE L · 2014 to 2018
$10.7M
Integrating data, algorithms and clinical reasoning for surgical risk assessmentR01GM110240 · NIGMS · UNIVERSITY OF FLORIDA · PI BIHORAC, AZRA, RASHIDI, PARISA · 2016 to 2025
$5.1M
Hematopoietic Stem Cell Dysfunction in the Elderly after Severe InjuryR01GM113945 · NIGMS · UNIVERSITY OF FLORIDA · PI EFRON, PHILIP A · 2015 to 2019
$1.6M
Aligning Patient Acuity with Intensity of Care after SurgeryK23GM140268 · NIGMS · UNIVERSITY OF FLORIDA · PI LOFTUS, TYLER J · 2020 to 2023
$619k
NIGMS NIH HHS K23 GM140268NIGMS NIH HHS P50 GM111152NIGMS NIH HHS R01 GM110240NIGMS NIH HHS R01 GM113945
6 · The paper itself

Abstract

Background: There is sparse high-level evidence to guide treatment decisions for severe, acute cholecystitis (inflammation of the gallbladder). Therefore, treatment decisions depend heavily on individual surgeon judgment, which is highly variable and potentially amenable to personalized, data-driven decision support. We test the hypothesis that surgeons' treatment recommendations misalign with perceived risks and benefits for laparoscopic cholecystectomy (surgical removal) vs. percutaneous cholecystostomy (image-guided drainage). Methods: Surgery attendings, fellows, and residents applied individual judgement to standardized case scenarios in a live, web-based survey in estimating the quantitative risks and benefits of laparoscopic cholecystectomy vs. percutaneous cholecystostomy for both moderate and severe acute cholecystitis, as well as the likelihood that they would recommend cholecystectomy. Results: Surgeons predicted similar 30-day morbidity rates for laparoscopic cholecystectomy and percutaneous cholecystostomy. However, a greater proportion of surgeons predicted low (<50%) likelihood of full recovery following percutaneous cholecystostomy compared with cholecystectomy for both moderate (30% vs. 2%, Conclusions: Surgeon recommendations for severe cholecystitis were discordant with perceived risks and benefits of treatment options. Surgeons predicted greater functional recovery after cholecystectomy but less than one-third recommended cholecystectomy. These findings suggest opportunities to augment surgical decision-making with personalized, data-driven decision support.

Indexed as

cholecystectomycholecystitischolecystostomycomplicationsriskssurgical decision making

Identifiers

PMID36339515
PMCPMC9632988
OpenAlexW4295928416

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.