ArticleFrontiers in endocrinology2022
Implications of metabolic health status and obesity on the risk of kidney cancer: A nationwide population-based cohort study.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Association of metabolic obesity phenotypes with risk of overall and site-specific cancers: a systematic review and meta-analysis of cohort studies.British journal of cancer · 2024Pooled it
- Exploring the mechanisms of serum miRNA in obesity-related kidney injury.International urology and nephrology · 2026Review
- Metabolic Phenotypes and the Risk of Cancer Occurrence: A Prospective Cohort Study with 18-Year Follow-up.Journal of obesity & metabolic syndrome · 2026Article
- Metabolic Syndrome Components and Cancer Risk in Normal-Weight Subjects: Systematic Review and Meta-Analysis in over 18 Million Individuals.Journal of clinical medicine · 2026Review
- Association of diabetes risk reduction diet (DRRD) score with metabolic health, brain-derived neurotrophic factor and adropin in Iranian adults.Nutrition journal · 2025Article
- Correlation between metabolic unhealth and prostate cancer -an inverse probability weighting study.BMC urology · 2025Article
- Dynamic phenotypes of preclinical and clinical obesity in relation to new-onset cancer risk: A longitudinal analysis from the UK biobank.Diabetes, obesity & metabolism · 2025Article
- Metabolic Phenotype and Risk of Obesity-Related Cancers in the Women's Health Initiative.Cancer prevention research (Philadelphia, Pa.) · 2025Article
- Rising Trends in Metabolically Healthy Obesity in Cancer Patients and Its Impact on Cardiovascular Events: Insights from a Contemporary Nationwide Analysis in the USA (2016-2020).Journal of clinical medicine · 2024Article
- Nutrient patterns in relation to metabolic health status and serum levels of brain-derived neurotrophic factor (BDNF) and adropin in adults.Scientific reports · 2024Article
- Transitions in metabolic syndrome and metabolic obesity status over time and risk of urologic cancer: A prospective cohort study.PloS one · 2024Article
- Update on Adipose Tissue and Cancer.Endocrine reviews · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study evaluated the association between metabolic health status and incident kidney cancer among obese participants. Materials and methods: A total of 514,866 individuals were included from the Korean National Health Insurance Service-National Health Screening Cohort. Changes in metabolic health status and obesity from the baseline examination in 2009-2010 to the next biannual examination in 2011-2012 were determined. Based on the status change, obese participants were divided into four groups: stable metabolically healthy obesity, metabolically healthy obesity to metabolically unhealthy obesity, metabolically unhealthy obesity to metabolically healthy obesity, and stable metabolically unhealthy obesity. Results: The stable metabolically healthy obesity phenotype did not confer an increased risk of incident kidney cancer, compared to the stable metabolically healthy non-obese group. In contrast, the metabolically healthy obesity to metabolically unhealthy obesity group had a significantly higher risk of incident kidney cancer than the stable metabolically healthy non-obese group. Among patients with metabolically unhealthy obesity at baseline, those who transitioned to the metabolically healthy obese group had no increased risk of kidney cancer, whereas those who remained in metabolically unhealthy obesity status had a higher risk of incident kidney cancer than the stable metabolically healthy non-obese group. The transition or maintenance of metabolic health was a decisive factor for kidney cancer in obese patients. Conclusions: Maintaining or restoring metabolic health should be stressed upon in obese patients to reduce the risk of kidney cancer.
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