Evidence map›Paper›PMID 36339329›Full record

ArticleNewborn (Clarksville, Md.)

Use of Fresh-frozen Plasma in Newborn Infants.

Manvi Tyagi, Akhil Maheshwari, Brunetta Guaragni, Mario Motta

Open access · bronzeAbstract read
In one paragraph

Article in Newborn (Clarksville, Md.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Hereditary Antithrombin Deficiency in Pediatric Patients: Pathophysiology, Clinical Features, Diagnosis, and Antithrombin Replacement Therapy.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Manvi TyagiDepartment of Pediatrics, Augusta University, Georgia, United States of America.
Akhil MaheshwariWeatherby Healthcare, Fort Lauderdale, Florida, United States of America.
Brunetta GuaragniNeonatologia e Terapia Intensiva Neonatale, ASST Spedali Civili di Brescia, Italy.
Mario MottaNeonatologia e Terapia Intensiva Neonatale, ASST Spedali Civili di Brescia, Italy.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAugusta University · US

Funding

Effect of Platelet Transfusions on Neonatal Intestinal InjuryR01HL133022 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI KRISHNAN, MOHAN KUMAR · 2017 to 2020
$1.6M
NHLBI NIH HHS R01 HL133022
6 · The paper itself

Abstract

Nearly 10% of premature and critically ill infants receive fresh-frozen plasma (FFP) transfusions to reduce their high risk of bleeding. The authors have only limited data to identify relevant clinical predictors of bleeding and to evaluate the efficacy of FFP administration. There is still no consensus on the optimal use of FFP in infants who have abnormal coagulation parameters but are not having active bleeding. The aims of this review are to present current evidence derived from clinical studies focused on the use of FFP in neonatology and then use these data to propose best practice recommendations for the safety of neonates receiving FFP.

Indexed as

Coagulation testsDisseminated intravascular coagulationFresh-frozen plasmaHemorrhagesPlasmapheresisRelative riskWhole-blood donor units

Identifiers

PMID36339329
PMCPMC9631350
OpenAlexW4303418611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.