Evidence map›Paper›PMID 36339306›Full record

ArticleMovement disorders clinical practice2022

The Gray Area of Freezing of Gait Annotation: A Guideline and Open-Source Practical Tool.

Helena Cockx, Emilie Klaver, Marleen Tjepkema-Cloostermans, Richard van Wezel, Jorik Nonnekes

Open access · hybridAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Japanese translation of lindop parkinson's disease mobility assessment (LPA): validity and reliability study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. An updated definition of freezing of gait.Nature reviews. Neurology · 2026
    Review
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  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Helena CockxDepartment of Biophysics Radboud University, Donders Institute for Brain, Cognition and Behaviour Nijmegen The Netherlands.ORCID https://orcid.org/0000-0001-7782-7178
Emilie KlaverDepartment of Biophysics Radboud University, Donders Institute for Brain, Cognition and Behaviour Nijmegen The Netherlands.ORCID https://orcid.org/0000-0003-1082-5527
Marleen Tjepkema-CloostermansDepartment of Neurology and Clinical Neurophysiology Medical Spectrum Twente Enschede The Netherlands.ORCID https://orcid.org/0000-0002-0686-7284
Richard van WezelDepartment of Biophysics Radboud University, Donders Institute for Brain, Cognition and Behaviour Nijmegen The Netherlands.ORCID https://orcid.org/0000-0001-5753-7069
Jorik NonnekesDepartment of Rehabilitation; Centre of Expertise for Parkinson & Movement Disorders Radboud University Medical Centre; Donders Institute for Brain, Cognition and Behaviour Nijmegen The Netherlands.ORCID https://orcid.org/0000-0003-2434-1427
Radboud University Nijmegen · NLMedisch Spectrum Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Freezing of gait, a disabling episodic symptom, is difficult to assess as the exact begin- and endpoint of an episode is not easy to specify. This hampers scientific and clinical progress. The current golden standard is video annotation by two independent raters. However, the comparison of the two ratings gives rise to non-overlapping, gray areas. Objective: To provide a guideline for dealing with these gray areas. Methods/Results: We propose a standardized procedure for handling the gray areas based on two parameters, the tolerance and correction parameter. Furthermore, we recommend the use of positive agreement, negative agreement, and prevalence index to report interrater agreement instead of the commonly used intraclass correlation coefficient or Cohen's kappa. This theoretical guideline was implemented in an open-source practical tool, Conclusion: This paper aims to contribute to the standardization of freezing of gait assessment, thereby improving data sharing procedures and replicability of study results

Indexed as

freezing of gaitstandardizationvideo annotations

Identifiers

PMID36339306
PMCPMC9631855
OpenAlexW4294192143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.