Evidence map›Paper›PMID 36339223›Full record

ReviewFrontiers in public health2022

A global review of racial, ethnic and socio-economic disparities in multisystem inflammatory syndrome in children related to COVID-19.

Zoha Asghar, Kanza Sharaf, Faran Ahmed Butt, Omer Ahmed Shaikh, Manahil Shekha, Abdul Waris, Irfan Ullah, Abdulqadir J Nashwan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
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  6. Article
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  9. Review
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  11. Article
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  14. The New Era of mRNA Vaccines: The Success of the COVID-19 Vaccines and the Safety Concerns in Adolescents.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Zoha AsgharDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Kanza SharafDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Faran Ahmed ButtDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Omer Ahmed ShaikhDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Manahil ShekhaDepartment of Medicine, Ziauddin University, Karachi, Pakistan.
Abdul WarisKabir Medical College, Gandhara University, Peshawar, Pakistan.
Irfan UllahKabir Medical College, Gandhara University, Peshawar, Pakistan.
Abdulqadir J NashwanHamad Medical Corporation, Doha, Qatar.
Ziauddin University · PKGandhara University · PKHamad Medical Corporation · QAKhyber Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With over 500 million confirmed cases and 6.2 million deaths worldwide, the novel coronavirus has highlighted the underlying disparities in healthcare, unpreparedness to deal with a new disease and the need for monitoring and surveillance for a post-infectious syndrome as well as complicated diseases. Initially, children were thought to be spared but reports of a new phenomenon manifesting as Kawasaki-like disease, toxic shock syndrome, and multi-system inflammatory syndrome, which developed after a few weeks of severe COVID-19 infection, emerged in the pediatric population. As the pandemic progressed, increased prevalence of multi-system inflammatory syndrome in children (MIS-C) related to COVID-19 was seen in non-Hispanic blacks, Asians, and Latinos as compared to the white population drawing attention to a possible role of ethnicity and socio-economic disparities. The CDC currently reports that 31% of MIS-C cases were seen in Black Non-Hispanics and 26% in Latinos, who were historically more affected in previous pandemics. Furthermore, MIS-C cases in developing countries showed higher mortality as compared to high-income countries, which points toward the role of social determinants of health and limitations in a low-resource set up in increasing the disease burden of MIS-C, which should be treated as a public health emergency. Our review highlights the role of ethnicity, socio-economic factors, comorbidities, and differences in populations affected by MIS-C in high-income vs. low- and middle-income countries.

Indexed as

COVID-19ChildEthnicityHumansPandemicsSocioeconomic FactorsSystemic Inflammatory Response SyndromechildrenCOVID-19health disparitiesinfantKawasaki diseasemulti-system inflammatory syndromepediatric multi-system inflammatory syndromeSARS CoV-2

Identifiers

PMID36339223
PMCPMC9632619
OpenAlexW4306925041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.